The RPUSD4 Polyclonal Antibody (CAB15538) is a valuable tool for researchers studying RPUSD4, a protein involved in mitochondrial RNA processing and stability. This antibody, produced in rabbits, has been validated for use in Western blot applications and is highly reactive with human samples. By binding to the RPUSD4 protein, this antibody enables the detection and analysis of RPUSD4 in a variety of cell types, making it ideal for studies in mitochondrial biology and RNA metabolism.RPUSD4 plays a crucial role in ensuring the proper processing and stability of mitochondrial RNA, which is essential for the production of functional mitochondrial proteins.
Dysregulation of RPUSD4 has been implicated in various mitochondrial disorders and diseases, making it an important target for research in the fields of bioenergetics and human genetics. By investigating the function and regulation of RPUSD4, researchers can gain insights into mitochondrial dysfunction and potentially develop new therapeutic strategies for mitochondrial-related diseases.
Product Name:
RPUSD4 Rabbit Polyclonal Antibody
SKU:
CAB15538
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-377 of human RPUSD4 (NP_116184.2).
Enables mitochondrial ribosomal large subunit rRNA binding activity; pseudouridine synthase activity; and tRNA binding activity. Involved in mitochondrial tRNA pseudouridine synthesis and positive regulation of mitochondrial translation. Located in mitochondrion; nucleoplasm; and ribonucleoprotein granule.
Purification Method:
Affinity purification
Gene ID:
84881
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates using RPUSD4 Rabbit pAb (CAB15538) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 90S.
