The RPTOR Polyclonal Antibody (CAB16309) is a crucial tool for researchers studying the mTOR pathway, which plays a key role in regulating cell growth, survival, and metabolism. This antibody, raised in rabbits, specifically targets the RPTOR protein, a key component of the mTOR complex. Validated for use in Western blot applications, it allows for the detection and analysis of RPTOR in various cell types.RPTOR, also known as Regulatory-Associated Protein of mTOR, is involved in the regulation of cell growth and nutrient signaling. Dysfunction in the mTOR pathway has been implicated in various diseases, including cancer, diabetes, and neurodegenerative disorders.
The RPTOR Polyclonal Antibody is essential for studying the role of RPTOR in these diseases and for developing potential therapeutic interventions targeting the mTOR pathway.Overall, the RPTOR Polyclonal Antibody is a valuable tool for researchers investigating the complexities of the mTOR pathway and its implications in various disease states. Its high reactivity with human samples and specificity for RPTOR make it a reliable choice for immunology and cancer research studies.
Product Name:
Raptor Rabbit Polyclonal Antibody
SKU:
CAB16309
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 888-1013 of human RPTOR (NP_065812.1).
This gene encodes a component of a signaling pathway that regulates cell growth in response to nutrient and insulin levels. The encoded protein forms a stoichiometric complex with the mTOR kinase, and also associates with eukaryotic initiation factor 4E-binding protein-1 and ribosomal protein S6 kinase. The protein positively regulates the downstream effector ribosomal protein S6 kinase, and negatively regulates the mTOR kinase. Multiple transcript variants encoding different isoforms have been found for this gene.
Purification Method:
Affinity purification
Gene ID:
57521
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300,50% glycerol,pH7.3.
Western blot analysis of lysates from Rat brain, using Raptor Rabbit pAb (CAB16309) at 1:500 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25ug per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 90s.
