The RPTN Antibody (PAC02564) is a valuable tool for researchers studying RPTN, a protein involved in skin barrier function and epidermal differentiation. This polyclonal antibody, produced in rabbits, is specifically designed for detecting RPTN in human samples and is validated for use in Western blot applications.RPTN is known for its role in maintaining skin integrity and preventing water loss, making it a key player in skin health and barrier function. Dysregulation of RPTN expression has been linked to skin disorders such as ichthyosis and atopic dermatitis, highlighting its importance in skin biology research.
By targeting the RPTN protein, researchers can investigate its role in skin disorders and epidermal development, providing insights that may lead to the development of new therapeutic strategies for skin conditions. The RPTN Antibody (PAC02564) offers a reliable tool for analyzing RPTN expression in various cell types, making it an essential component in studies focusing on skin biology and dermatological research.
Antibody Name:
RPTN Antibody (PACO22564)
Antibody SKU:
PACO22564
Size:
100ul
Host Species:
Rabbit
Tested Applications:
ELISA, WB
Recommended Dilutions:
ELISA:1:2000-1:10000, WB:1:500-1:3000
Species Reactivity:
Human
Immunogen:
Synthesized peptide derived from C-terminal of human RPTN.
Form:
Liquid
Storage Buffer:
Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Purification Method:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Clonality:
Polyclonal
Isotype:
IgG
Conjugate:
Non-conjugated
Western blot analysis of extracts from HeLa cells, using RPTN antibody.
Background:
Involved in the cornified cell envelope formation. Multifunctional epidermal matrix protein. Reversibly binds calcium.
Synonyms:
Repetin; RPTN;
UniProt Protein Function:
Involved in the cornified cell envelope formation. Multifunctional epidermal matrix protein. Reversibly binds calcium.
