The RPS6KB2 Polyclonal Antibody (CAB1541) is a valuable tool for researchers studying the protein RPS6KB2, which is known to be involved in various cellular processes, including cell growth, proliferation, and survival. This antibody is produced by immunizing rabbits with a specific antigen, resulting in high reactivity and specificity for human samples.Validated for use in Western blot applications, the RPS6KB2 Polyclonal Antibody binds specifically to the RPS6KB2 protein, allowing for accurate detection and analysis in a variety of cell types.
This makes it an ideal choice for studies in the fields of cancer research, cell biology, and signal transduction.Given the role of RPS6KB2 in cellular processes such as cell cycle progression and protein synthesis, understanding its function is crucial for unraveling its involvement in diseases like cancer and metabolic disorders. By utilizing the RPS6KB2 Polyclonal Antibody, researchers can gain valuable insights into the mechanisms underlying these conditions, ultimately paving the way for the development of targeted therapies.
Product Name:
p70 S6 Kinase 2 Rabbit Polyclonal Antibody
SKU:
CAB1541
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-170 of human p70 S6 Kinase 2 (NP_003943.2).
Sequence:
MAAV FDLD LETE EGSE GEGE PELS PADA CPLA ELRA AGLE PVGH YEEV ELTE TSVN VGPE RIGP HCFE LLRV LGKG GYGK VFQV RKVQ GTNL GKIY AMKV LRKA KIVR NAKD TAHT RAER NILE SVKH PFIV ELAY AFQT GGKL YLIL ECLS GGEL FTHL EREG IFLE DT
This gene encodes a member of the RSK (ribosomal S6 kinase) family of serine/threonine kinases. This kinase contains a kinase catalytic domain and phosphorylates the S6 ribosomal protein and eukaryotic translation initiation factor 4B (eIF4B). Phosphorylation of S6 leads to an increase in protein synthesis and cell proliferation.
Purification Method:
Affinity purification
Gene ID:
6199
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of extracts of various cell lines, using p70 S6 Kinase 2 antibody (CAB1541) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 60s.
