The RPS6KB1 Polyclonal Antibody (CAB2190) is a valuable tool for researchers studying the RPS6KB1 protein, a key regulator of cell growth and proliferation. This antibody, raised in rabbits, exhibits high reactivity with human samples and is validated for use in Western blot applications. By specifically binding to RPS6KB1, this antibody enables precise detection and analysis of the protein in a variety of cell types, making it an excellent choice for studies in molecular biology and cancer research.RPS6KB1, also known as ribosomal protein S6 kinase beta-1, is a critical player in signaling pathways that control protein synthesis and cell survival.
Dysregulation of RPS6KB1 activity has been implicated in various diseases, including cancer, diabetes, and neurodegenerative disorders. Investigating the role of RPS6KB1 in these conditions is essential for developing targeted therapies and understanding disease mechanisms at the molecular level.With its high specificity and sensitivity, the RPS6KB1 Polyclonal Antibody (CAB2190) provides researchers with a powerful tool for exploring the functions and potential therapeutic applications of RPS6KB1 in health and disease.
Product Name:
p70 S6 Kinase 1 Rabbit Polyclonal Antibody
SKU:
CAB2190
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 421-520 of human p70 S6 Kinase 1 (NP_003152.1).
This gene encodes a member of the ribosomal S6 kinase family of serine/threonine kinases. The encoded protein responds to mTOR (mammalian target of rapamycin) signaling to promote protein synthesis, cell growth, and cell proliferation. Activity of this gene has been associated with human cancer. Alternatively spliced transcript variants have been observed. The use of alternative translation start sites results in isoforms with longer or shorter N-termini which may differ in their subcellular localizations. There are two pseudogenes for this gene on chromosome 17.
Purification Method:
Affinity purification
Gene ID:
6198
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.09% Sodium azide,50% glycerol,pH7.3.
Western blot analysis of various lysates using p70 S6 Kinase 1 Rabbit pAb (CAB2190) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 5s.
