The RPS6KB1 Polyclonal Antibody (CAB16968) is a valuable tool for researchers studying RPS6KB1, a critical intracellular signaling molecule involved in the regulation of cell growth and survival. This antibody, produced in rabbits, shows high specificity and sensitivity for RPS6KB1 in human samples and is validated for use in Western blot applications.RPS6KB1, also known as p70S6 kinase, is a key mediator of the mTOR signaling pathway and plays a crucial role in coordinating protein synthesis and cell proliferation. Dysregulation of RPS6KB1 activity has been implicated in various diseases, including cancer, diabetes, and neurodegenerative disorders.
By targeting RPS6KB1, researchers can gain insights into the molecular mechanisms underlying these conditions and potentially identify novel therapeutic strategies.With its excellent performance in detecting RPS6KB1 protein expression, the CAB16968 antibody is an essential tool for scientists investigating the role of RPS6KB1 in health and disease. By facilitating the analysis of RPS6KB1 levels in different cell types and experimental conditions, this antibody allows for precise and reliable experimental results, ultimately advancing our understanding of RPS6KB1 function and its potential as a therapeutic target.
Product Name:
p70 S6 Kinase 1 Rabbit Polyclonal Antibody
SKU:
CAB16968
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 426-525 of human P70 S6K (NP_003152.1).
This gene encodes a member of the ribosomal S6 kinase family of serine/threonine kinases. The encoded protein responds to mTOR (mammalian target of rapamycin) signaling to promote protein synthesis, cell growth, and cell proliferation. Activity of this gene has been associated with human cancer. Alternatively spliced transcript variants have been observed. The use of alternative translation start sites results in isoforms with longer or shorter N-termini which may differ in their subcellular localizations. There are two pseudogenes for this gene on chromosome 17.
Purification Method:
Affinity purification
Gene ID:
6198
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates using p70 S6 Kinase 1 Rabbit pAb (CAB16968) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 1s.
