The RPS6KB1 Polyclonal Antibody (CAB16658) is specifically designed for research involving RPS6KB1, a protein kinase involved in cell growth and proliferation. This antibody, produced in rabbits, is highly reactive with human samples and has been validated for use in Western blot applications. It binds specifically to the RPS6KB1 protein, allowing for accurate detection and analysis in a variety of cell types.RPS6KB1, also known as p70 S6 kinase, is a key player in the mTOR signaling pathway, which regulates cell growth, survival, and metabolism. Dysregulation of RPS6KB1 has been associated with various diseases, including cancer, diabetes, and neurological disorders.
Research into the function and regulation of RPS6KB1 is essential for understanding its role in these conditions and developing targeted therapies.This antibody is an invaluable tool for researchers studying cell signaling pathways, growth control, and disease mechanisms. Its high specificity and sensitivity make it ideal for use in immunology, oncology, and metabolic research. By elucidating the role of RPS6KB1 in cellular processes, this antibody can contribute to advancements in therapeutic strategies for a range of diseases.
Product Name:
p70 S6 Kinase 1 Rabbit Polyclonal Antibody
SKU:
CAB16658
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 426-525 of human P70 S6K (NP_003152.1).
This gene encodes a member of the ribosomal S6 kinase family of serine/threonine kinases. The encoded protein responds to mTOR (mammalian target of rapamycin) signaling to promote protein synthesis, cell growth, and cell proliferation. Activity of this gene has been associated with human cancer. Alternatively spliced transcript variants have been observed. The use of alternative translation start sites results in isoforms with longer or shorter N-termini which may differ in their subcellular localizations. There are two pseudogenes for this gene on chromosome 17.
Purification Method:
Affinity purification
Gene ID:
6198
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates using p70 S6 Kinase 1 Rabbit pAb (CAB16658) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 1s.
