The RPS6KA4 Polyclonal Antibody (CAB10130) is a key tool for researchers studying RPS6KA4, a protein involved in cell signaling pathways and gene regulation. This antibody, produced in rabbits, exhibits high specificity and sensitivity towards human samples, and has been validated for use in Western blot applications. By binding to the RPS6KA4 protein, this antibody enables accurate detection and analysis in a variety of cell types, making it an invaluable resource for studies in molecular biology and cancer research.RPS6KA4, also known as ribosomal protein S6 kinase alpha-4, plays a crucial role in regulating cell growth, proliferation, and differentiation.
Dysregulation of RPS6KA4 has been implicated in various diseases, including cancer, metabolic disorders, and neurodegenerative conditions. By investigating the function of RPS6KA4, researchers can gain insights into the underlying mechanisms of these diseases and potentially identify new therapeutic targets for intervention. The RPS6KA4 Polyclonal Antibody is a valuable tool for further elucidating the role of RPS6KA4 in cellular processes and disease pathology.
Product Name:
RPS6KA4 Rabbit Polyclonal Antibody
SKU:
CAB10130
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 673-772 of human RPS6KA4 (NP_003933.1).
This gene encodes a member of the RSK (ribosomal S6 kinase) family of serine/threonine kinases. This kinase contains 2 non-identical kinase catalytic domains and phosphorylates various substrates, including CREB1 and ATF1. The encoded protein can also phosphorylate histone H3 to regulate certain inflammatory genes. Several transcript variants encoding different isoforms have been found for this gene.
Purification Method:
Affinity purification
Gene ID:
8986
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300,50% glycerol,pH7.3.
Western blot analysis of lysates from U-87MG cells, using RPS6KA4 Rabbit pAb (CAB10130) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 180s.
