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RPS3 Rabbit Monoclonal Antibody (CAB4872)

SKU:
CAB4872
Product Type:
Antibody
Antibody Type:
Monoclonal Antibody
Reactivity:
Human
Mouse
Rat
Host Species:
Rabbit
Isotype:
IgG
Synonyms:
S3
Research Area:
Cell Death
  • Cell Death Antibodies 2 Anti-RPS3 Antibody CAB4872
  • Cell Death Antibodies 2 Anti-RPS3 Antibody CAB4872
$167 - $503
Frequently bought together:

Description

system_update_altDatasheetsystem_update_altMSDS
Product Name:RPS3 Rabbit Monoclonal Antibody
SKU:CAB4872
Size:20uL, 100uL
Isotype:IgG
Host Species:Rabbit
Reactivity:Human,Mouse,Rat
Immunogen:A synthetic peptide corresponding to a sequence within amino acids 100-200 of human RPS3 (P23396).
Sequence:AQAE SLRY KLLG GLAV RRAC YGVL RFIM ESGA KGCE VVVS GKLR GQRA KSMK FVDG LMIH SGDP VNYY VDTA VRHV LLRQ GVLG IKVK IMLP WDPT GKIG P
Tested Applications:WB IF/ICC ELISA
Recommended Dilution:WB,1:500 - 1:2000 IF/ICC,1:50 - 1:200
Synonyms:S3; uS3; RPS3
Positive Sample:HeLa,HT-29,Mouse liver,Mouse spleen,Mouse pancreas,Rat lung
Conjugate:Unconjugated
Cellular Localization:Cytoplasm, Mitochondrion inner membrane, Nucleus, Peripheral membrane protein, cytoskeleton, nucleolus, spindle.
Calculated MW:27kDa
Observed MW:27kDa

Ribosomes, the organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit. Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins. This gene encodes a ribosomal protein that is a component of the 40S subunit, where it forms part of the domain where translation is initiated. The protein belongs to the S3P family of ribosomal proteins. Studies of the mouse and rat proteins have demonstrated that the protein has an extraribosomal role as an endonuclease involved in the repair of UV-induced DNA damage. The protein appears to be located in both the cytoplasm and nucleus but not in the nucleolus. Higher levels of expression of this gene in colon adenocarcinomas and adenomatous polyps compared to adjacent normal colonic mucosa have been observed. This gene is co-transcribed with the small nucleolar RNA genes U15A and U15B, which are located in its first and fifth introns, respectively. As is typical for genes encoding ribosomal proteins, there are multiple processed pseudogenes of this gene dispersed through the genome. Multiple alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Purification Method:Affinity purification
Gene ID:6188
Clone Number:ARC0302
Storage Buffer:Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3.
Product ImageWestern blot analysis of extracts of various cell lines, using RPS3 Rabbit mAb (CAB4872) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 1s.

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