The RPS3 Polyclonal Antibody (CAB13543) is a valuable tool for researchers studying RPS3, a ribosomal protein with diverse functions in cellular processes. This antibody, generated in rabbits, exhibits high specificity and sensitivity towards RPS3 in human samples, making it ideal for Western blot applications. By binding to RPS3, this antibody enables precise detection and analysis in various cell types, facilitating studies in molecular biology, cell biology, and cancer research.RPS3 is a key player in protein synthesis and ribosome biogenesis, with implications in cell growth, proliferation, and differentiation. Dysregulation of RPS3 has been linked to various diseases, including cancer, neurodegenerative disorders, and metabolic conditions.
Investigating the role of RPS3 using this antibody can provide insights into the mechanisms underlying these pathologies, paving the way for the development of targeted therapies.Overall, the RPS3 Polyclonal Antibody (CAB13543) offers researchers a reliable tool for exploring the functions and dysregulation of RPS3 in health and disease. Its high specificity and versatility make it a valuable asset in uncovering novel insights into cellular processes and pathways associated with RPS3, opening new avenues for therapeutic interventions.
Product Name:
RPS3 Rabbit Polyclonal Antibody
SKU:
CAB13543
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-243 of human RPS3 (NP_000996.2).
Ribosomes, the organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit. Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins. This gene encodes a ribosomal protein that is a component of the 40S subunit, where it forms part of the domain where translation is initiated. The protein belongs to the S3P family of ribosomal proteins. Studies of the mouse and rat proteins have demonstrated that the protein has an extraribosomal role as an endonuclease involved in the repair of UV-induced DNA damage. The protein appears to be located in both the cytoplasm and nucleus but not in the nucleolus. Higher levels of expression of this gene in colon adenocarcinomas and adenomatous polyps compared to adjacent normal colonic mucosa have been observed. This gene is co-transcribed with the small nucleolar RNA genes U15A and U15B, which are located in its first and fifth introns, respectively. As is typical for genes encoding ribosomal proteins, there are multiple processed pseudogenes of this gene dispersed through the genome. Multiple alternatively spliced transcript variants encoding different isoforms have been found for this gene.
Purification Method:
Affinity purification
Gene ID:
6188
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of extracts of various cell lines, using RPS3 antibody (CAB13543) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.
