The RPS27A Polyclonal Antibody (PAC021668) is a valuable tool for researchers studying RPS27A, a protein involved in protein degradation and regulation. This antibody, generated in rabbits, exhibits high reactivity with human samples and has been validated for use in Western blot applications. By specifically binding to the RPS27A protein, this antibody enables accurate detection and analysis in a variety of cell types, making it an essential component for studies in cell biology and protein degradation mechanisms.RPS27A, also known as ubiquitin-40S ribosomal protein S27a, plays a crucial role in targeting proteins for degradation through the ubiquitin-proteasome system. Its involvement in protein turnover and regulation makes it a key player in maintaining cellular homeostasis and responding to stress conditions.
Research on RPS27A is integral to understanding how cells regulate protein levels and function, with implications for diseases related to protein misfolding and aggregation.By using the RPS27A Polyclonal Antibody, researchers can gain valuable insights into the functions and regulation of RPS27A in various cellular processes. This antibody is a powerful tool for elucidating the role of RPS27A in protein degradation pathways, offering new possibilities for therapeutic interventions targeting protein homeostasis in disease states.
Antibody Name:
RPS27A Antibody (PACO21668)
Antibody SKU:
PACO21668
Size:
100ul
Host Species:
Rabbit
Tested Applications:
ELISA, IHC
Recommended Dilutions:
ELISA:1:2000-1:10000, IHC:1:50-1:100
Species Reactivity:
Human, Mouse
Immunogen:
Synthesized peptide derived from Internal of human Ubiquitin.
Form:
Liquid
Storage Buffer:
Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Purification Method:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen
Clonality:
Polyclonal
Conjugate:
Non-conjugated
Immunohistochemistry analysis of paraffin-embedded human breast carcinoma tissue, using Ubiquitin antibody.
Synonyms:
RPS27A; UBA52; UBA80; UBB; UBC
UniProt Protein Function:
UniProt Protein Details:
NCBI Summary:
Ubiquitin is a highly conserved nuclear and cytoplasmic protein that has a major role in targeting cellular proteins for degradation by the 26S proteosome. It is also involved in the maintenance of chromatin structure, the regulation of gene expression, and the stress response. Ubiquitin is synthesized as a precursor protein consisting of either polyubiquitin chains or a single ubiquitin moiety fused to an unrelated protein. This gene encodes a fusion protein consisting of ubiquitin at the N terminus and ribosomal protein L40 at the C terminus, a C-terminal extension protein (CEP). Multiple processed pseudogenes derived from this gene are present in the genome. [provided by RefSeq, Jul 2008]
