RPS19 Rabbit Monoclonal Antibody (CAB3675)
- SKU:
- CAB3675
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Research Area:
- Cell Biology
Description
Product Name: | RPS19 Rabbit Monoclonal Antibody |
SKU: | CAB3675 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse,Rat |
Immunogen: | A synthetic peptide corresponding to a sequence within amino acids 66-145 of human RPS19 (P39019). |
Sequence: | LRGG AGVG SMTK IYGG RQRN GVMP SHFS RGSK SVAR RVLQ ALEG LKMV EKDQ DGGR KLTP QGQR DLDR IAGQ VAAA NKKH |
Tested Applications: | WB IF/ICC IP ELISA |
Recommended Dilution: | WB,1:500 - 1:2000 IF/ICC,1:50 - 1:200 IP,0.5μg-4μg antibody for 200μg-400μg extracts of whole cells |
Synonyms: | DBA; S19; DBA1; eS19; LOH19CR1; RPS19 |
Positive Sample: | HT-29,293T,K-562,Mouse liver,Mouse brain,Mouse kidney,Rat liver,Rat spleen,Rat kidney,293F |
Conjugate: | Unconjugated |
Cellular Localization: | Nucleus, Cytoplasm |
Calculated MW: | 16kDa |
Observed MW: | 16kDa/ |
Ribosomes, the organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit. Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins. This gene encodes a ribosomal protein that is a component of the 40S subunit. The protein belongs to the S19E family of ribosomal proteins. It is located in the cytoplasm. Mutations in this gene cause Diamond-Blackfan anemia (DBA), a constitutional erythroblastopenia characterized by absent or decreased erythroid precursors, in a subset of patients. This suggests a possible extra-ribosomal function for this gene in erythropoietic differentiation and proliferation, in addition to its ribosomal function. Higher expression levels of this gene in some primary colon carcinomas compared to matched normal colon tissues has been observed. As is typical for genes encoding ribosomal proteins, there are multiple processed pseudogenes of this gene dispersed through the genome.
Purification Method: | Affinity purification |
Gene ID: | 6223 |
Clone Number: | ARC0820 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3. |