The RPS18 Polyclonal Antibody (CAB11687) is a valuable tool for researchers studying RPS18, a ribosomal protein essential for protein synthesis. This antibody, generated in rabbits, demonstrates high reactivity with human samples and is validated for use in Western blot applications. By specifically binding to the RPS18 protein, this antibody enables the detection and analysis of RPS18 in a variety of cell types, making it an excellent choice for studies in molecular biology and cancer research.RPS18 is a key component of the ribosome, the cellular machinery responsible for protein production.
Dysregulation of RPS18 has been implicated in various diseases, including cancer and genetic disorders. By studying the function and expression of RPS18, researchers can gain important insights into the mechanisms of protein synthesis and disease development.Overall, the RPS18 Polyclonal Antibody is a critical tool for investigating the role of RPS18 in cellular processes and disease pathology. Its high specificity and sensitivity make it a valuable asset for scientists seeking to deepen their understanding of protein synthesis and its implications for health and disease.
Product Name:
RPS18 Rabbit Polyclonal Antibody
SKU:
CAB11687
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-152 of human RPS18 (NP_072045.1).
Ribosomes, the organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit. Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins. This gene encodes a ribosomal protein that is a component of the 40S subunit. The protein belongs to the S13P family of ribosomal proteins. It is located in the cytoplasm. The gene product of the E. coli ortholog (ribosomal protein S13) is involved in the binding of fMet-tRNA, and thus, in the initiation of translation. This gene is an ortholog of mouse Ke3. As is typical for genes encoding ribosomal proteins, there are multiple processed pseudogenes of this gene dispersed through the genome.
Purification Method:
Affinity purification
Gene ID:
6222
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates using RPS18 Rabbit pAb (CAB11687) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 30s.