RPS15 Antibody (PACO49982)
- SKU:
- PACO49982
- Product Type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- ELISA
- WB
- IHC
- IF
- Antibody Type:
- Polyclonal Antibody
- Conjugation:
- Unconjugated
Description
RPS15 Antibody (PACO49982)
The RPS15 Antibody (PAC049982) is a polyclonal antibody designed for research involving ribosomal protein S15 (RPS15), a critical component of the ribosome. This antibody, raised in rabbits, is highly reactive with human samples and has been validated for use in various applications, including Western blotting.RPS15 is essential for protein synthesis and translation within cells, making it a key player in cellular growth and function. Research on RPS15 is crucial for understanding its role in various diseases, including cancer, where dysregulation of protein synthesis can lead to uncontrolled cell growth.
By targeting RPS15 with this antibody, researchers can detect and analyze its expression in different cell types, providing valuable insights into its function and potential therapeutic implications.With its high specificity and sensitivity, the RPS15 Antibody is a valuable tool for studies in molecular biology, cancer research, and beyond. By investigating the role of RPS15 in cellular processes, researchers can further our understanding of disease mechanisms and potentially uncover new targets for intervention.
| Antibody Name: | RPS15 Antibody (PACO49982) |
| Antibody SKU: | PACO49982 |
| Size: | 50ug |
| Host Species: | Rabbit |
| Tested Applications: | ELISA, WB, IHC, IF |
| Recommended Dilutions: | ELISA:1:2000-1:10000, WB:1:500-1:5000, IHC:1:20-1:200, IF:1:50-1:200 |
| Species Reactivity: | Human |
| Immunogen: | Recombinant Human 40S ribosomal protein S15 protein (63-137AA) |
| Form: | Liquid |
| Storage Buffer: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, pH 7.4 |
| Purification Method: | >95%, Protein G purified |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Conjugate: | Non-conjugated |
 | Western Blot. Positive WB detected in: Hela whole cell lysate. All lanes: RPS15 antibody at 4µg/ml. Secondary. Goat polyclonal to rabbit IgG at 1/50000 dilution. Predicted band size: 18 kDa. Observed band size: 18 kDa.. |
 | Immunohistochemistry of paraffin-embedded human spleen tissue using PACO49982 at dilution of 1:100. |
 | Immunohistochemistry of paraffin-embedded human lung cancer using PACO49982 at dilution of 1:100. |
| Background: | cytoplasm, cytosol, cytosolic small ribosomal subunit, focal adhesion, membrane, nucleoplasm, nucleus, DNA binding, poly(A) RNA binding, structural constituent of ribosome |
| Synonyms: | 40S ribosomal protein S15 (RIG protein) (Small ribosomal subunit protein uS19), RPS15, RIG |
| UniProt Protein Function: | RPS15: a ribosomal protein that is a component of the 40S subunit. The protein belongs to the S19P family of ribosomal proteins. It is located in the cytoplasm. This gene has been found to be activated in various tumors, such as insulinomas, esophageal cancers, and colon cancers. As is typical for genes encoding ribosomal proteins, there are multiple processed pseudogenes of this gene dispersed through the genome. [provided by RefSeq, Jul 2008] |
| UniProt Protein Details: | Protein type:Ribosomal; RNA-binding Chromosomal Location of Human Ortholog: 19p13.3 Cellular Component: cytoplasm; cytosol; focal adhesion; membrane; nucleoplasm Molecular Function:protein binding; structural constituent of ribosome Biological Process: mRNA catabolic process, nonsense-mediated decay; osteoblast differentiation; ribosomal small subunit assembly and maintenance; ribosomal small subunit biogenesis and assembly; ribosomal small subunit export from nucleus; rRNA processing; SRP-dependent cotranslational protein targeting to membrane; translation; translational initiation; viral transcription |
| NCBI Summary: | Ribosomes, the organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit. Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins. This gene encodes a ribosomal protein that is a component of the 40S subunit. The protein belongs to the S19P family of ribosomal proteins. It is located in the cytoplasm. This gene has been found to be activated in various tumors, such as insulinomas, esophageal cancers, and colon cancers. As is typical for genes encoding ribosomal proteins, there are multiple processed pseudogenes of this gene dispersed through the genome. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Apr 2015] |
| UniProt Code: | P62841 |
| NCBI GenInfo Identifier: | 51338641 |
| NCBI Gene ID: | 6209 |
| NCBI Accession: | P62841.2 |
| UniProt Secondary Accession: | P62841,P11174, Q3KRA1, Q9UDC2, A5D8V9, |
| UniProt Related Accession: | P62841 |
| Molecular Weight: | 17,040 Da |
| NCBI Full Name: | 40S ribosomal protein S15 |
| NCBI Synonym Full Names: | ribosomal protein S15 |
| NCBI Official Symbol: | RPS15Â Â |
| NCBI Official Synonym Symbols: | RIG; S15Â Â |
| NCBI Protein Information: | 40S ribosomal protein S15 |
| UniProt Protein Name: | 40S ribosomal protein S15 |
| UniProt Synonym Protein Names: | RIG protein |
| Protein Family: | 30S ribosomal protein |
| UniProt Gene Name: | RPS15Â Â |
| UniProt Entry Name: | RS15_HUMAN |
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