The RPS12 Polyclonal Antibody (CAB5890) is a valuable tool for research involving ribosomal protein S12, a critical component of the ribosomal complex responsible for protein synthesis. This antibody, raised in rabbits, exhibits high reactivity with human samples and is validated for use in Western blot applications. By binding to the RPS12 protein, researchers can detect and analyze its expression in various cell types, making it ideal for studies in molecular biology and protein synthesis research.RPS12 is essential for ribosomal function, playing a key role in the translation of genetic information into functional proteins. Dysregulation of RPS12 has been linked to various diseases, including cancer and genetic disorders.
Studying the expression and function of RPS12 can provide insights into its role in these conditions and may uncover potential therapeutic targets for intervention.By utilizing the RPS12 Polyclonal Antibody in research settings, scientists can further investigate the intricate mechanisms of protein synthesis and its implications in disease pathology. This antibody offers a reliable tool for exploring the role of RPS12 in cellular processes, aiding in the advancement of scientific knowledge and potential drug development strategies.
Product Name:
RPS12 Rabbit Polyclonal Antibody
SKU:
CAB5890
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-132 of human RPS12 (NP_001007.2).
Ribosomes, the organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit. Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins. This gene encodes a ribosomal protein that is a component of the 40S subunit. The protein belongs to the S12E family of ribosomal proteins. It is located in the cytoplasm. Increased expression of this gene in colorectal cancers compared to matched normal colonic mucosa has been observed. As is typical for genes encoding ribosomal proteins, there are multiple processed pseudogenes of this gene dispersed through the genome.
Purification Method:
Affinity purification
Gene ID:
6206
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of extracts of various cell lines, using RPS12 antibody (CAB5890) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 15s.
