The RPS11 Polyclonal Antibody (PAC004965) is a valuable tool for researchers studying RPS11, a ribosomal protein involved in protein synthesis. This antibody, produced in rabbits, exhibits high reactivity with human samples and has been validated for use in Western blot applications. By specifically binding to the RPS11 protein, this antibody enables precise detection and analysis in various cell types, making it an ideal choice for studies in molecular biology and cancer research.RPS11 is a key component of the ribosome, playing a crucial role in the translation of mRNA into proteins. Dysregulation of RPS11 has been implicated in various diseases, including cancer and genetic disorders.
By investigating the function and expression of RPS11, researchers can gain insights into the mechanisms underlying these conditions and potentially identify novel therapeutic targets.Overall, the RPS11 Polyclonal Antibody offers a reliable tool for researchers seeking to explore the roles of RPS11 in cellular processes and disease pathogenesis. Its high specificity and sensitivity make it a valuable asset in advancing our understanding of protein synthesis and its implications in health and disease.
Antibody Name:
RPS11 Antibody
Antibody SKU:
PACO04965
Size:
50ug
Host Species:
Rabbit
Tested Applications:
ELISA, WB, IHC
Recommended Dilutions:
WB:1:500-1:2000, IHC:1:100-1:300
Species Reactivity:
Human, Mouse, Rat
Immunogen:
synthesized peptide derived from the Internal region of human Ribosomal Protein S11.
Form:
Liquid
Storage Buffer:
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Purification Method:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Clonality:
Polyclonal
Isotype:
IgG
Conjugate:
Non-conjugated
Synonyms:
RPS11; 40S ribosomal protein S11
UniProt Protein Function:
RPS11: a member of the S17P family of ribosomal proteins that is a component of the 40S subunit. This gene is co-transcribed with the small nucleolar RNA gene U35B, which is located in the third intron. As is typical for genes encoding ribosomal proteins, there are multiple processed pseudogenes of this gene dispersed throughout the genome. [provided by RefSeq, Jul 2012]Protein type: Ribosomal; RNA-binding; TranslationChromosomal Location of Human Ortholog: 19q13.3Cellular Component: cytoplasm; cytosol; focal adhesion; membrane; nucleolus; nucleoplasmMolecular Function: protein binding; structural constituent of ribosomeBiological Process: mRNA catabolic process, nonsense-mediated decay; rRNA processing; SRP-dependent cotranslational protein targeting to membrane; translation; translational initiation; viral transcription
UniProt Protein Details:
NCBI Summary:
Ribosomes, the organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit. Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins. This gene encodes a member of the S17P family of ribosomal proteins that is a component of the 40S subunit. This gene is co-transcribed with the small nucleolar RNA gene U35B, which is located in the third intron. As is typical for genes encoding ribosomal proteins, there are multiple processed pseudogenes of this gene dispersed throughout the genome. [provided by RefSeq, Jul 2012]
