The RPS10 Polyclonal Antibody (CAB6056) is a valuable tool for researchers studying RPS10, a key protein involved in ribosome biogenesis and protein synthesis. This antibody, produced in rabbits, demonstrates high reactivity with human samples and is validated for use in Western blot applications. By specifically binding to the RPS10 protein, this antibody enables accurate detection and analysis in a variety of cell types, making it an essential component for studies in molecular biology and cancer research.RPS10, a ribosomal protein, plays a crucial role in the assembly and functioning of ribosomes, the cellular machinery responsible for protein synthesis.
Dysregulation of RPS10 has been linked to various diseases, including cancer, neurodegenerative disorders, and developmental abnormalities. Understanding the functions and regulatory mechanisms of RPS10 is vital for unraveling the molecular processes involved in these pathological conditions and for developing targeted therapies to treat them. The RPS10 Polyclonal Antibody provides researchers with a reliable tool for investigating the role of RPS10 in health and disease, ultimately advancing our understanding of cellular processes and potential treatment options.
Product Name:
RPS10 Rabbit Polyclonal Antibody
SKU:
CAB6056
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-165 of human RPS10 (NP_001190174.1).
Ribosomes, the organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit. Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins. This gene encodes a ribosomal protein that is a component of the 40S subunit. The protein belongs to the S10E family of ribosomal proteins. It is located in the cytoplasm. Variable expression of this gene in colorectal cancers compared to adjacent normal tissues has been observed, although no correlation between the level of expression and the severity of the disease has been found. As is typical for genes encoding ribosomal proteins, there are multiple processed pseudogenes of this gene dispersed through the genome. Alternate splicing results in multiple transcript variants that encode the same protein. Naturally occurring read-through transcription occurs between this locus and the neighboring locus NUDT3 (nudix (nucleoside diphosphate linked moiety X)-type motif 3).
Purification Method:
Affinity purification
Gene ID:
6204
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of various lysates, using RPS10 Rabbit pAb (CAB6056) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 20s.
