The RPRD1A Polyclonal Antibody (CAB15854) is a valuable tool for researchers studying RPRD1A, a protein involved in RNA processing and transcriptional regulation. This antibody, generated in rabbits, specifically targets RPRD1A and is highly reactive with human samples. Validated for use in Western blot applications, it enables the detection and analysis of RPRD1A in various cell types.RPRD1A is known to play a critical role in gene expression regulation, making it a key target for studies in molecular biology and cancer research.
By understanding the function of RPRD1A, researchers can gain insights into how gene expression is controlled and regulated, potentially leading to the development of novel therapeutic approaches for diseases such as cancer.Overall, the RPRD1A Polyclonal Antibody (CAB15854) is a valuable reagent for researchers looking to explore the role of RPRD1A in gene expression and transcriptional regulation, offering a powerful tool for advancing our understanding of molecular mechanisms in various biological processes.
Product Name:
RPRD1A Rabbit Polyclonal Antibody
SKU:
CAB15854
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 47-276 of human RPRD1A (NP_001290341.1).
nucleoplasm, nucleus, RNA polymerase II, holoenzyme
Calculated MW:
36kDa
Observed MW:
36kDa
This gene encodes a cell-cycle and transcription regulatory protein. The encoded protein interacts with the cell cycle inhibitor cyclin-dependent kinase 4 inhibitor B and may function as a negative regulator of G(1)/S phase progression. This protein also forms homo- and hetrodimers with the protein, regulation of nuclear pre-mRNA domain-containing protein 1B, to form a scaffold that interacts with the C-terminal domain of RNA polymerase II subunit B1 and regulates several aspects of transcription. Alternate splicing results in multiple transcript variants. A pseudogene of this gene is found on chromosome 16.
Purification Method:
Affinity purification
Gene ID:
55197
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates using RPRD1A Rabbit pAb (CAB15854) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 10s.
