The RPP30 Polyclonal Antibody (CAB8479) is a valuable tool for researchers studying RPP30, a protein involved in RNA processing and splicing. This polyclonal antibody, produced in rabbits, exhibits high reactivity with human samples and is validated for use in Western blot applications. By binding to the RPP30 protein, this antibody enables precise detection and analysis in a variety of cell types, making it ideal for investigations in molecular biology and gene expression research.
RPP30 plays a crucial role in RNA metabolism by participating in the formation of the RNA cleavage and polyadenylation complex. Dysregulation of RPP30 has been implicated in various diseases, including cancer and neurodegenerative disorders, underscoring its importance in cellular processes. By elucidating the function and expression of RPP30, researchers can gain insights into the pathogenesis of these conditions and potentially uncover novel therapeutic targets for intervention.
Product Name:
RPP30 Rabbit Polyclonal Antibody
SKU:
CAB8479
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-268 of human RPP30 (NP_006404.1).
Enables ribonuclease P RNA binding activity. Contributes to ribonuclease P activity. Involved in tRNA 5'-leader removal. Part of multimeric ribonuclease P complex and ribonuclease MRP complex.
Purification Method:
Affinity purification
Gene ID:
10556
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of various lysates using RPP30 Rabbit pAb (CAB8479) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 90s.
