The RPP25 Polyclonal Antibody (CAB9973) is a valuable tool for researchers studying RPP25, a key component of the RNase P complex involved in RNA processing. This antibody, produced in rabbits, is specifically designed for use in Western blot applications and is highly reactive with human samples.RPP25 is essential for the cleavage of precursor tRNAs, making it an important player in the regulation of gene expression. Dysregulation of RPP25 has been implicated in various diseases, including cancer and neurodegenerative disorders.
By targeting RPP25 with this antibody, researchers can gain insight into its role in these conditions and potentially identify new therapeutic targets.The RPP25 Polyclonal Antibody enables precise detection and analysis of RPP25 protein levels in different cell types, offering a versatile tool for studies in molecular biology and disease mechanisms. Its high specificity and sensitivity make it a reliable choice for researchers looking to deepen their understanding of RNA processing and its implications for human health.
Product Name:
RPP25 Rabbit Polyclonal Antibody
SKU:
CAB9973
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-199 of human RPP25 (NP_060263.2).
Enables ribonuclease P RNA binding activity. Contributes to ribonuclease P activity. Involved in tRNA 5'-leader removal. Located in centriolar satellite and nucleoplasm. Part of multimeric ribonuclease P complex and ribonuclease MRP complex. Biomarker of autistic disorder.
Purification Method:
Affinity purification
Gene ID:
54913
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of various lysates using RPP25 Rabbit pAb (CAB9973) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Enhanced Kit (AbGn00021).Exposure time: 90s.
