The RPLP2 Polyclonal Antibody (CAB6974) is a valuable tool for researchers studying RPLP2, a key protein involved in ribosome biogenesis and protein synthesis. This antibody, produced in rabbits, has high reactivity with human samples and has been validated for Western blot applications. By binding specifically to the RPLP2 protein, this antibody enables precise detection and analysis in a variety of cell types, making it ideal for studies in molecular biology and cancer research.RPLP2 plays a crucial role in ribosomal function and cellular proliferation, making it a promising target for investigation in various diseases, including cancer.
Understanding the mechanisms by which RPLP2 impacts protein synthesis and cell growth is essential for advancing our knowledge of these processes and developing potential targeted therapies. The RPLP2 Polyclonal Antibody is a valuable tool for researchers seeking to explore the function and implications of RPLP2 in cellular biology and disease pathology.
Product Name:
RPLP2 Rabbit Polyclonal Antibody
SKU:
CAB6974
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-115 of human RPLP2 (NP_000995.1).
Ribosomes, the organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit. Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins. This gene encodes a ribosomal phosphoprotein that is a component of the 60S subunit. The protein, which is a functional equivalent of the E. coli L7/L12 ribosomal protein, belongs to the L12P family of ribosomal proteins. It plays an important role in the elongation step of protein synthesis. Unlike most ribosomal proteins, which are basic, the encoded protein is acidic. Its C-terminal end is nearly identical to the C-terminal ends of the ribosomal phosphoproteins P0 and P1. The P2 protein can interact with P0 and P1 to form a pentameric complex consisting of P1 and P2 dimers, and a P0 monomer. The protein is located in the cytoplasm. As is typical for genes encoding ribosomal proteins, there are multiple processed pseudogenes of this gene dispersed through the genome.
Purification Method:
Affinity purification
Gene ID:
6181
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Immunohistochemistry analysis of paraffin-embedded Human colon carcinoma using RPLP2 Rabbit pAb (CAB6974) at dilution of 1:500 (40x lens). Perform high pressure antigen retrieval with 10 mM citrate buffer pH 6.0 before commencing with IHC staining protocol.
