RPLP1 Rabbit Polyclonal Antibody (CAB6725)
- SKU:
- CAB6725
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Fish - Zebrafish
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Biology
Description
Product Name: | RPLP1 Rabbit Polyclonal Antibody |
SKU: | CAB6725 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse,Rat,Zebrafish |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-114 of human RPLP1 (NP_000994.1). |
Sequence: | MASV SELA CIYS ALIL HDDE VTVT EDKI NALI KAAG VNVE PFWP GLFA KALA NVNI GSLI CNVG AGGP APAA GAAP AGGP APST AAAP AEEK KVEA KKEE SEES DDDM GFGL FD |
Tested Applications: | WB IF/ICC ELISA |
Recommended Dilution: | WB,1:500 - 1:2000 IF/ICC,1:50 - 1:100 |
Synonyms: | P1; LP1; RPP1; RPLP1 |
Positive Sample: | SW480,Mouse spleen,Mouse lung,Mouse brain,Rat spleen,Rat lung,Rat brain |
Conjugate: | Unconjugated |
Cellular Localization: | cytoplasm, cytosol, cytosolic ribosome, focal adhesion |
Calculated MW: | 12kDa |
Observed MW: | 17kDa |
Ribosomes, the organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit. Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins. This gene encodes a ribosomal phosphoprotein that is a component of the 60S subunit. The protein, which is a functional equivalent of the E. coli L7/L12 ribosomal protein, belongs to the L12P family of ribosomal proteins. It plays an important role in the elongation step of protein synthesis. Unlike most ribosomal proteins, which are basic, the encoded protein is acidic. Its C-terminal end is nearly identical to the C-terminal ends of the ribosomal phosphoproteins P0 and P2. The P1 protein can interact with P0 and P2 to form a pentameric complex consisting of P1 and P2 dimers, and a P0 monomer. The protein is located in the cytoplasm. Two alternatively spliced transcript variants that encode different proteins have been observed. As is typical for genes encoding ribosomal proteins, there are multiple processed pseudogenes of this gene dispersed through the genome.
Purification Method: | Affinity purification |
Gene ID: | 6176 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3. |