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RPL7A Rabbit Polyclonal Antibody (CAB13713)

SKU:
CAB13713
Product Type:
Antibody
Reactivity:
Human
Mouse
Rat
Host Species:
Rabbit
Isotype:
IgG
Antibody Type:
Polyclonal Antibody
Research Area:
Cell Biology
  • Cell Biology Antibodies 4 Anti-RPL7A Antibody CAB13713
  • Cell Biology Antibodies 4 Anti-RPL7A Antibody CAB13713
  • Cell Biology Antibodies 4 Anti-RPL7A Antibody CAB13713
$167 - $503
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Description

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RPL7A Rabbit Polyclonal Antibody (CAB13713)

The RPL7A Polyclonal Antibody (CAB13713) is a valuable tool for research involving the RPL7A protein. RPL7A, also known as Ribosomal Protein L7a, is a component of the ribosome and plays a crucial role in protein synthesis. This polyclonal antibody is raised in rabbits and is highly reactive with human samples, making it an excellent choice for researchers studying protein expression in various cell types. The antibody is validated for use in Western blot applications, allowing for accurate detection and analysis of the RPL7A protein.The RPL7A Polyclonal Antibody (CAB13713) enables researchers to investigate the role of RPL7A in cellular processes and diseases such as cancer, where dysregulation of protein synthesis can have profound effects on cell growth and proliferation.

By understanding the function of RPL7A, researchers can gain insights into the molecular mechanisms underlying disease pathology and potentially identify new therapeutic targets.Overall, the RPL7A Polyclonal Antibody (CAB13713) is a valuable tool for researchers interested in studying protein synthesis, ribosome function, and the role of RPL7A in various biological processes. Its high reactivity and reliability in Western blot applications make it an essential reagent for scientific investigations in the fields of molecular biology and cell biology.

Product Name:RPL7A Rabbit Polyclonal Antibody
SKU:CAB13713
Size:20uL, 100uL
Isotype:IgG
Host Species:Rabbit
Reactivity:Human,Mouse,Rat
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 1-266 of human RPL7A (NP_000963.1).
Sequence:MPKG KKAK GKKV APAP AVVK KQEA KKVV NPLF EKRP KNFG IGQD IQPK RDLT RFVK WPRY IRLQ RQRA ILYK RLKV PPAI NQFT QALD RQTA TQLL KLAH KYRP ETKQ EKKQ RLLA RAEK KAAG KGDV PTKR PPVL RAGV NTVT TLVE NKKA QLVV IAHD VDPI ELVV FLPA LCRK MGVP YCII KGKA RLGR LVHR KTCT TVAF TQVN SEDK GALA KLVE AIRT NYND RYDE IRRH WGGN VLGP KSVA RIAK LEKA KAKE LATK LG
Tested Applications:WB IF/ICC ELISA
Recommended Dilution:WB,1:500 - 1:2000 IF/ICC,1:50 - 1:100
Synonyms:L7A; eL8; TRUP; SURF3; RPL7A
Positive Sample:A-549,A-431,HeLa,U-87MG,Jurkat,MCF7,Mouse kidney,Mouse liver
Conjugate:Unconjugated
Cellular Localization:cytoplasm, cytosol, cytosolic ribosome, focal adhesion, nucleolus, nucleus
Calculated MW:30kDa
Observed MW:35kDa

Cytoplasmic ribosomes, organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit. Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins. This gene encodes a ribosomal protein that is a component of the 60S subunit. The protein belongs to the L7AE family of ribosomal proteins. It can interact with a subclass of nuclear hormone receptors, including thyroid hormone receptor, and inhibit their ability to transactivate by preventing their binding to their DNA response elements. This gene is included in the surfeit gene cluster, a group of very tightly linked genes that do not share sequence similarity. It is co-transcribed with the U24, U36a, U36b, and U36c small nucleolar RNA genes, which are located in its second, fifth, fourth, and sixth introns, respectively. This gene rearranges with the trk proto-oncogene to form the chimeric oncogene trk-2h, which encodes an oncoprotein consisting of the N terminus of ribosomal protein L7a fused to the receptor tyrosine kinase domain of trk. As is typical for genes encoding ribosomal proteins, there are multiple processed pseudogenes of this gene dispersed through the genome.

Purification Method:Affinity purification
Gene ID:6130
Storage Buffer:Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Product ImageWestern blot analysis of various lysates using RPL7A Rabbit pAb (CAB13713) at 1:3000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 90s.

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