RPL7 Rabbit Polyclonal Antibody (CAB5932)
- SKU:
- CAB5932
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Biology
Description
Product Name: | RPL7 Rabbit Polyclonal Antibody |
SKU: | CAB5932 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse,Rat |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-248 of human RPL7 (NP_000962.2). |
Sequence: | MEGV EEKK KEVP AVPE TLKK KRRN FAEL KIKR LRKK FAQK MLRK ARRK LIYE KAKH YHKE YRQM YRTE IRMA RMAR KAGN FYVP AEPK LAFV IRIR GING VSPK VRKV LQLL RLRQ IFNG TFVK LNKA SINM LRIV EPYI AWGY PNLK SVNE LIYK RGYG KINK KRIA LTDN ALIA RSLG KYGI ICME DLIH EIYT VGKR FKEA NNFL WPFK LSSP RGGM KKKT THFV EGGD AGNR EDQI NRLI RRMN |
Tested Applications: | WB IHC-P IF/ICC ELISA |
Recommended Dilution: | WB,1:500 - 1:2000 IHC-P,1:50 - 1:100 IF/ICC,1:50 - 1:100 |
Synonyms: | L7; uL30; humL7-1; RPL7 |
Positive Sample: | A-549,MCF7,A375,HeLa,293T,Mouse kidney,Mouse liver |
Conjugate: | Unconjugated |
Cellular Localization: | cytoplasm, cytosol, cytosolic ribosome, focal adhesion, nucleolus, nucleus |
Calculated MW: | 29kDa |
Observed MW: | 29kDa |
Ribosomes, the organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit. Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins. This gene encodes a ribosomal protein that is a component of the 60S subunit. The protein belongs to the L30P family of ribosomal proteins. It contains an N-terminal basic region-leucine zipper (BZIP)-like domain and the RNP consensus submotif RNP2. In vitro the BZIP-like domain mediates homodimerization and stable binding to DNA and RNA, with a preference for 28S rRNA and mRNA. The protein can inhibit cell-free translation of mRNAs, suggesting that it plays a regulatory role in the translation apparatus. It is located in the cytoplasm. The protein has been shown to be an autoantigen in patients with systemic autoimmune diseases, such as systemic lupus erythematosus. As is typical for genes encoding ribosomal proteins, there are multiple processed pseudogenes of this gene dispersed through the genome.
Purification Method: | Affinity purification |
Gene ID: | 6129 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3. |