The RPL27A Polyclonal Antibody (PAC01439) is a valuable tool for researchers studying RPL27A, a ribosomal protein essential for protein synthesis. This antibody, generated in rabbits, is highly specific to human RPL27A and is validated for use in Western blot applications. It detects the RPL27A protein, allowing for its identification and analysis in various cell types. RPL27A is a crucial component of the ribosome, the cellular machinery responsible for protein production. As such, it plays a pivotal role in cell growth, proliferation, and overall protein synthesis.
Dysregulation of RPL27A has been implicated in various diseases, including cancer and neurodegenerative disorders, making it an attractive target for further research.By using the RPL27A Polyclonal Antibody, researchers can gain insights into the expression and function of RPL27A in different biological contexts. This antibody is an essential tool for studies in molecular biology, cancer research, and other fields where protein synthesis and ribosomal function are of interest.
Antibody Name:
RPL27A Antibody
Antibody SKU:
PACO01439
Size:
50ug
Host Species:
Rabbit
Tested Applications:
ELISA, WB, IHC, IF
Recommended Dilutions:
WB:1:500-1:2000, IHC:1:100-1:300, IF:1:200-1:1000
Species Reactivity:
Human, Mouse, Rat
Immunogen:
synthesized peptide derived from the C-terminal region of human Ribosomal Protein L27A.
Form:
Liquid
Storage Buffer:
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Purification Method:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Clonality:
Polyclonal
Isotype:
IgG
Conjugate:
Non-conjugated
Synonyms:
RPL27A; 60S ribosomal protein L27a
UniProt Protein Function:
RPL27A: a ribosomal protein that is a component of the 60S subunit. The protein belongs to the L15P family of ribosomal proteins. It is located in the cytoplasm. Variable expression of this gene in colorectal cancers compared to adjacent normal tissues has been observed, although no correlation between the level of expression and the severity of the disease has been found. As is typical for genes encoding ribosomal proteins, multiple processed pseudogenes derived from this gene are dispersed through the genome. [provided by RefSeq, Jul 2008]Protein type: Ribosomal; TranslationChromosomal Location of Human Ortholog: 11p15Cellular Component: cytosol; membraneMolecular Function: protein binding; RNA bindingBiological Process: mRNA catabolic process, nonsense-mediated decay; rRNA processing; SRP-dependent cotranslational protein targeting to membrane; translational initiation; viral transcription
UniProt Protein Details:
NCBI Summary:
Ribosomes, the organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit. Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins. This gene encodes a ribosomal protein that is a component of the 60S subunit. The protein belongs to the L15P family of ribosomal proteins. It is located in the cytoplasm. Variable expression of this gene in colorectal cancers compared to adjacent normal tissues has been observed, although no correlation between the level of expression and the severity of the disease has been found. As is typical for genes encoding ribosomal proteins, multiple processed pseudogenes derived from this gene are dispersed through the genome. [provided by RefSeq, Jul 2008]
