The RPL23A Polyclonal Antibody (CAB4086) is a research tool designed for studies involving RPL23A, a ribosomal protein that plays a crucial role in protein synthesis. This antibody, produced in rabbits, is highly specific for human samples and has been validated for use in Western blot applications. By targeting the RPL23A protein, this antibody facilitates the detection and analysis of RPL23A expression in various cell types, making it an ideal tool for research in molecular biology and cancer biology.RPL23A is a key component of the ribosome, the cellular machinery responsible for translating genetic information into functional proteins. Dysregulation of RPL23A has been implicated in various diseases, including cancer, where alterations in protein synthesis can drive tumor growth and progression.
By studying the function and expression of RPL23A, researchers can gain valuable insights into the molecular mechanisms underlying disease pathology and potentially identify novel therapeutic targets.This RPL23A Polyclonal Antibody offers researchers a reliable and specific tool for investigating the role of RPL23A in cellular processes and disease states. With its high reactivity and sensitivity, this antibody enables accurate detection and quantification of RPL23A levels, facilitating in-depth exploration of its functions and potential implications for human health.
Product Name:
RPL23A Rabbit Polyclonal Antibody
SKU:
CAB4086
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-156 of human RPL23A (NP_000975.2).
Ribosomes, the organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit. Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins. This gene encodes a ribosomal protein that is a component of the 60S subunit. The protein belongs to the L23P family of ribosomal proteins. It is located in the cytoplasm. The protein may be one of the target molecules involved in mediating growth inhibition by interferon. In yeast, the corresponding protein binds to a specific site on the 26S rRNA. This gene is co-transcribed with the U42A, U42B, U101A, and U101B small nucleolar RNA genes, which are located in its third, first, second, and fourth introns, respectively. As is typical for genes encoding ribosomal proteins, there are multiple processed pseudogenes of this gene dispersed through the genome.
Purification Method:
Affinity purification
Gene ID:
6147
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of various lysates using RPL23A Rabbit pAb (CAB4086) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 10s.
