[KO Validated] RPL22 Rabbit Polyclonal Antibody (CAB9202)
- SKU:
- CAB9202
- Product Type:
- Antibody
- Applications:
- WB
- Reactivity:
- Human
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Research Area:
- Cell Biology
Description
Product Name: | [KO Validated] RPL22 Rabbit Polyclonal Antibody |
SKU: | CAB9202 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse,Rat |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-122 of human RPL22 (NP_000974.1). |
Sequence: | MAPV KKLV VKGG KKKK QVLK FTLD CTHP VEDG IMDA ANFE QFLQ ERIK VNGK AGNL GGGV VTIE RSKS KITV TSEV PFSK RYLK YLTK KYLK KNNL RDWL RVVA NSKE SYEL RYFQ INQD EE |
Tested Applications: | WB IHC-P ELISA |
Recommended Dilution: | WB,1:1000 - 1:5000 IHC-P,1:50 - 1:100 |
Synonyms: | EAP; L22; HBP15; HBP15/L22; 22 |
Positive Sample: | 293T,HeLa,U-87MG,HepG2,Jurkat |
Conjugate: | Unconjugated |
Cellular Localization: | cytoplasm, cytosol, cytosolic ribosome, extracellular exosome, focal adhesion, nucleus |
Calculated MW: | 15kDa |
Observed MW: | 15kDa |
Ribosomes, the organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit. Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins. This gene encodes a cytoplasmic ribosomal protein that is a component of the 60S subunit. The protein belongs to the L22E family of ribosomal proteins. Its initiating methionine residue is post-translationally removed. The protein can bind specifically to Epstein-Barr virus-encoded RNAs (EBERs) 1 and 2. The mouse protein has been shown to be capable of binding to heparin. Transcript variants utilizing alternative polyA signals exist. As is typical for genes encoding ribosomal proteins, there are multiple processed pseudogenes of this gene dispersed through the genome. It was previously thought that this gene mapped to 3q26 and that it was fused to the acute myeloid leukemia 1 (AML1) gene located at 21q22 in some therapy-related myelodysplastic syndrome patients with 3;21 translocations; however, these fusions actually involve a ribosomal protein L22 pseudogene located at 3q26, and this gene actually maps to 1p36.3-p36.2.
Purification Method: | Affinity purification |
Gene ID: | 6146 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3. |