The RPL18A Polyclonal Antibody (CAB16967) is a vital tool for researchers studying RPL18A, a ribosomal protein essential for protein synthesis. This antibody, generated in rabbits, exhibits high specificity and sensitivity towards human samples, making it suitable for various research applications such as Western blotting.RPL18A is a crucial component of the ribosome, the cellular machinery responsible for translating genetic information into proteins. Dysregulation of RPL18A has been linked to various diseases, including cancer and neurodegenerative disorders, highlighting its potential as a therapeutic target.
By using the RPL18A Polyclonal Antibody, researchers can investigate the expression and function of RPL18A in different cell types and disease states, advancing our understanding of its role in health and disease.With its reliable performance and versatility, the RPL18A Polyclonal Antibody (CAB16967) is an indispensable tool for scientists conducting research in molecular biology, cell biology, and medicine. By enabling the detection and analysis of RPL18A, this antibody contributes to the development of novel strategies for diagnosing and treating diseases associated with ribosomal dysfunction.
Product Name:
RPL18A Rabbit Polyclonal Antibody
SKU:
CAB16967
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 50-176 of human RPL18A (NP_000971.1).
Ribosomes, the organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit. Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins. This gene encodes a member of the L18AE family of ribosomal proteins that is a component of the 60S subunit. The encoded protein may play a role in viral replication by interacting with the hepatitis C virus internal ribosome entry site (IRES). This gene is co-transcribed with the U68 snoRNA, located within the third intron. As is typical for genes encoding ribosomal proteins, there are multiple processed pseudogenes of this gene dispersed throughout the genome.
Purification Method:
Affinity purification
Gene ID:
6142
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates using RPL18A Rabbit pAb (CAB16967) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 1s.
