The RPL13 Polyclonal Antibody (CAB6723) is a valuable tool for researchers studying RPL13, a ribosomal protein involved in protein synthesis and cellular growth. This antibody, raised in rabbits, is highly specific for human samples and is validated for use in various applications, including Western blotting. By targeting the RPL13 protein, this antibody allows for the detection and analysis of RPL13 expression in a wide range of cell types, making it ideal for investigations in molecular biology and cancer research.RPL13 is essential for the proper functioning of ribosomes, the cellular machinery responsible for protein production.
Dysregulation of RPL13 expression has been linked to various diseases, including cancer and genetic disorders. By understanding the role of RPL13 in these conditions, researchers can uncover new therapeutic targets and potential treatment strategies. The RPL13 Polyclonal Antibody is a valuable tool for unraveling the complex mechanisms underlying these diseases and advancing our knowledge of cellular biology.
Product Name:
RPL13 Rabbit Polyclonal Antibody
SKU:
CAB6723
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-211 of human RPL13 (NP_150254.1).
Ribosomes, the organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit. Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins. This gene encodes a ribosomal protein that is a component of the 60S subunit. The protein belongs to the L13E family of ribosomal proteins. It is located in the cytoplasm. This gene is expressed at significantly higher levels in benign breast lesions than in breast carcinomas. Alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. As is typical for genes encoding ribosomal proteins, there are multiple processed pseudogenes of this gene dispersed through the genome.
Purification Method:
Affinity purification
Gene ID:
6137
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of various lysates using RPL13 Rabbit pAb (CAB6723) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 1s.