The RPL11 Polyclonal Antibody (CAB6407) is a valuable tool for researchers studying RPL11, a key protein involved in ribosome biogenesis and protein synthesis. This antibody, generated in rabbits, is highly specific to human RPL11 and has been validated for use in Western blot applications. By binding to the RPL11 protein, this antibody allows for the detection and analysis of RPL11 levels in various cell types, making it an essential component in studies focused on understanding the molecular mechanisms underlying protein synthesis and ribosome function.RPL11 is known to play a crucial role in regulating cell growth, proliferation, and apoptosis, making it a promising target for research in cancer biology and other cellular processes.
Dysregulation of RPL11 expression has been linked to various diseases, highlighting the importance of studying its function in different physiological and pathological conditions. By using the RPL11 Polyclonal Antibody, researchers can gain valuable insights into the role of RPL11 in cellular processes and potentially uncover novel therapeutic targets for a range of diseases.
Product Name:
RPL11 Rabbit Polyclonal Antibody
SKU:
CAB6407
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-177 of RPL11 (NP_001186731.1).
Ribosomes, the organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit. Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins. This gene encodes a ribosomal protein that is a component of the 60S subunit. The protein belongs to the L5P family of ribosomal proteins. It is located in the cytoplasm. The protein probably associates with the 5S rRNA. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. As is typical for genes encoding ribosomal proteins, there are multiple processed pseudogenes of this gene dispersed through the genome.
Purification Method:
Affinity purification
Gene ID:
6135
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of 293F, using RPL11 Rabbit pAb (CAB6407) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 90s.
