The RPL10L Antibody (PAC039606) is a polyclonal antibody designed for research involving RPL10L, a ribosomal protein that plays a critical role in protein synthesis. This antibody, raised in rabbits, is highly reactive with human samples and is validated for use in various applications including Western blot and immunohistochemistry.RPL10L, also known as ribosomal protein L10-like, is essential for ribosome function and is involved in regulating protein translation. It is a key player in the synthesis of proteins necessary for cell growth and proliferation.
Research into RPL10L can provide insights into various cellular processes, making it a valuable tool for studies in molecular biology, cell biology, and cancer research.Understanding the function and regulation of RPL10L is essential for uncovering its role in normal cellular function and disease processes. The RPL10L Antibody allows for the detection and analysis of RPL10L in various cell types, making it an ideal tool for researchers looking to explore the role of this ribosomal protein in different biological pathways.
Western blot. All lanes: RPL10L antibody at 4µg/ml. Lane 1: Jurkat whole cell lysate. Lane 2: Hela whole cell lysate. Lane 3: HL60 whole cell lysate. Lane 4: K562 whole cell lysate. Lane 5: Mouse liver tissue. Lane 6: MCF-7 whole cell lysate. Secondary. Goat polyclonal to rabbit IgG at 1/10000 dilution. Predicted band size: 25 kDa. Observed band size: 25 kDa.
Immunohistochemistry of paraffin-embedded human melanoma using PACO39606 at dilution of 1:100.
Immunohistochemistry of paraffin-embedded human cervical cancer using PACO39606 at dilution of 1:100.
Background:
May play a role in compensating for the inactivated X-linked gene during spermatogenesis.
Synonyms:
60S ribosomal protein L10-like (Large ribosomal subunit protein uL16-like), RPL10L
UniProt Protein Function:
RPL10L: May play a role in compensating for the inactivated X- linked gene during spermatogenesis. Belongs to the ribosomal protein L10e family.Protein type: Ribosomal; TranslationChromosomal Location of Human Ortholog: 14q21.2Cellular Component: membrane; nucleusMolecular Function: structural constituent of ribosomeBiological Process: ribosomal large subunit assembly and maintenance; spermatogenesis; translation
UniProt Protein Details:
NCBI Summary:
This gene encodes a protein sharing sequence similarity with ribosomal protein L10. It is not currently known whether the encoded protein is a functional ribosomal protein or whether it has evolved a function that is independent of the ribosome. This gene is intronless. [provided by RefSeq, Jul 2008]