The RPL10A Polyclonal Antibody (CAB5925) is designed for research involving RPL10A, a ribosomal protein known for its role in protein synthesis and cellular growth. The antibody, raised in rabbits, is highly specific and reactive with human, mouse, and rat samples, making it versatile for use in various applications such as Western blot and immunohistochemistry.RPL10A is a key player in ribosome assembly and function, essential for the translation of genetic information into proteins. Its involvement in cellular processes makes it a valuable target for research in molecular biology, cancer biology, and developmental biology.
By detecting and analyzing RPL10A expression, researchers can gain insights into how this protein contributes to normal cellular function and disease pathology.Overall, the RPL10A Polyclonal Antibody is a valuable tool for studying the function and regulation of RPL10A in different biological contexts, providing researchers with the ability to deepen their understanding of protein synthesis and its implications in health and disease.
Product Name:
RPL10A Rabbit Polyclonal Antibody
SKU:
CAB5925
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-110 of human RPL10A (NP_009035.3).
Ribosomes, the organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit. Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins. This gene encodes a ribosomal protein that is a component of the 60S subunit. The protein belongs to the L1P family of ribosomal proteins. It is located in the cytoplasm. The expression of this gene is downregulated in the thymus by cyclosporin-A (CsA), an immunosuppressive drug. Studies in mice have shown that the expression of the ribosomal protein L10a gene is downregulated in neural precursor cells during development. This gene previously was referred to as NEDD6 (neural precursor cell expressed, developmentally downregulated 6), but it has been renamed RPL10A (ribosomal protein 10a). As is typical for genes encoding ribosomal proteins, there are multiple processed pseudogenes of this gene dispersed through the genome.
Purification Method:
Affinity purification
Gene ID:
4736
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of various lysates using RPL10A Rabbit pAb (CAB5925) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Enhanced Kit (AbGn00021).Exposure time: 180s.
