The RPIA Polyclonal Antibody (PAC035194) is a valuable tool for researchers studying the RPIA protein, an enzyme involved in the pentose phosphate pathway. This rabbit-derived antibody is highly specific to human samples and has been validated for use in Western blot applications. By binding to the RPIA protein, this antibody allows for precise detection and analysis in a variety of cell types, making it an essential component in studies related to metabolism and cancer research.RPIA, also known as ribose-5-phosphate isomerase A, plays a crucial role in cell metabolism by catalyzing the interconversion of ribose-5-phosphate and ribulose-5-phosphate.
Dysregulation of RPIA has been linked to various diseases, including cancer, making it a promising target for therapeutic interventions. By delving into the functions of RPIA, researchers can gain insights into metabolic pathways and potentially identify new strategies for combating metabolic disorders and cancer progression.
Antibody Name:
rpiA Antibody (PACO35194)
Antibody SKU:
PACO35194
Size:
50ug
Host Species:
Rabbit
Tested Applications:
ELISA, WB
Recommended Dilutions:
ELISA:1:2000-1:10000, WB:1:1000-1:5000
Species Reactivity:
Escherichia coli
Immunogen:
Recombinant Escherichia coli Ribose-5-phosphate isomerase A protein (1-219AA)
Western blot. All lanes: rpiA antibody at 2µg/ml + DH5a whole cell lysate. Secondary. Goat polyclonal to rabbit IgG at 1/10000 dilution. Predicted band size: 23 kDa. Observed band size: 23 kDa.
Background:
Catalyzes the reversible conversion of ribose-5-phosphate to ribulose 5-phosphate
Synonyms:
Ribose-5-phosphate isomerase A (EC 5.3.1.6) (Phosphoriboisomerase A) (PRI), rpiA, ygfC
UniProt Protein Function:
Involved in the first step of the non-oxidative branch of the pentose phosphate pathway. It catalyzes the reversible conversion of ribose-5-phosphate to ribulose 5-phosphate. Can also act on D-ribose-5-diphosphate and D-ribose-5-triphosphate as substrate.
UniProt Protein Details:
NCBI Summary:
RpiA has similarity to an Edwardsiella ictaluri protein that provokes an immune response in catfish . [More information is available at EcoCyc: EG11443].
