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RPGRIP1 Polyclonal Antibody

SKU:
CAB24517
Product Type:
Antibody
Antibody Type:
Polyclonal Antibody
Reactivity:
Mouse
Rat
Host Species:
Rabbit
Isotype:
IgG
Applications:
IF
€129 - €359
Frequently bought together:

Description

RPGRIP1 Polyclonal Antibody (CAB24517)

RPGrip1 Polyclonal Antibody is a powerful tool for researchers investigating the role of RPGrip1 in cellular processes. RPGrip1, a key protein involved in ribosome biogenesis, plays a crucial role in the assembly and function of ribosomes, the cellular machinery responsible for protein synthesis. This antibody, produced in rabbits, exhibits high specificity and sensitivity towards RPGrip1 in human samples, making it ideal for use in Western blot applications.The ability of the RPGrip1 Polyclonal Antibody to recognize and bind to RPGrip1 enables researchers to study the expression levels and localization of this protein in various cell types. This is particularly valuable for investigations into fundamental cellular processes, such as ribosome biogenesis, and can provide insights into the mechanisms underlying diseases like cancer, where abnormalities in protein synthesis can contribute to tumor development.

By using the RPGrip1 Polyclonal Antibody, researchers can gain a deeper understanding of the molecular pathways involving RPGrip1, contributing to advancements in the fields of molecular biology, cancer research, and developmental biology. Its versatility and reliability make it a valuable tool for deciphering the complexities of ribosome biogenesis and its implications in health and disease.

Product Name:RPGRIP1 Polyclonal Antibody
Product Code:CAB24517
Reactivity:Mouse, Rat
Applications:Immunofluorescence
Host Species:Rabbit
Purification Method:Affinity purification
Isotype:IgG
Reactivity:Mouse, Rat
Tested Applications:IF/ICC, ELISA
Key Applications:Immunofluorescence
Recommended Dilution:IF/ICC 1:50-1:200
Storage Buffer:Store at -20°C. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300, 50% glycerol, pH7.3.
Cellular Location:Cell projection, cilium

This gene encodes a photoreceptor protein that interacts with retinitis pigmentosa GTPase regulator protein and is a key component of cone and rod photoreceptor cells. Mutations in this gene lead to autosomal recessive congenital blindness.

Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 1091-1286 of human RPGRIP1 (NP_065099.3).
Sequence:SEAQT TDSDD VIVPP MSQKY PKADS EKMCI EIVSL AFYPE AEVMS DENIK QVYVE YKFYD LPLSE TETPV SLRKP RAGEE IHFHF SKVID LDPQE QQGRR RFLFD MLNGQ DPDQG HLKFT VVSDP LDEEK KECEE VGYAY LQLWQ ILESG RDILE QELDI VSPED LATPI GRLKV SLQAA AVLHA IYKEM TEDLF S
Synonyms:RPGRIP1, CORD13, LCA6, RGI1, RGRIP, RPGRIP, RPGRIP1d, retinitis pigmentosa GTPase regulator interacting protein 1
Calculated MW:66kDa/70kDa/74kDa/76kDa/103kDa/146kDa
Observed MW:Refer to figures

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