RPGR Rabbit Polyclonal Antibody (CAB1844)
- SKU:
- CAB1844
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Research Area:
- Cell Biology
Frequently bought together:
Description
Product Name: | RPGR Rabbit Polyclonal Antibody |
SKU: | CAB1844 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse,Rat |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-260 of human RPGR (NP_001030025.1). |
Sequence: | MREP EELM PDSG AVFT FGKS KFAE NNPG KFWF KNDV PVHL SCGD EHSA VVTG NNKL YMFG SNNW GQLG LGSK SAIS KPTC VKAL KPEK VKLA ACGR NHTL VSTE GGNV YATG GNNE GQLG LGDT EERN TFHV ISFF TSEH KIKQ LSAG SNTS AALT EDGR LFMW GDNS EGQI GLKN VSNV CVPQ QVTI GKPV SWIS CGYY HSAF VTTD GELY VFGE PENG KLGL PNQL LGNH RTPQ LVSE IPEK VIQV ACGG EHTV VLTE |
Tested Applications: | WB IHC-P IF/ICC ELISA |
Recommended Dilution: | WB,1:100 - 1:500 IHC-P,1:50 - 1:200 IF/ICC,1:50 - 1:200 |
Synonyms: | CRD; RP3; COD1; PCDX; RP15; XLRP3; orf15; CORDX1; RPGR |
Positive Sample: | Mouse brain,Rat testis |
Conjugate: | Unconjugated |
Cellular Localization: | Cytoplasm, Golgi apparatus, centrosome, cilium axoneme, cilium basal body, cytoskeleton, flagellum axoneme, microtubule organizing center. |
Calculated MW: | 113kDa |
Observed MW: | 113kDa |
This gene encodes a protein with a series of six RCC1-like domains (RLDs), characteristic of the highly conserved guanine nucleotide exchange factors. The encoded protein is found in the Golgi body and interacts with RPGRIP1. This protein localizes to the outer segment of rod photoreceptors and is essential for their viability. Mutations in this gene have been associated with X-linked retinitis pigmentosa (XLRP). Multiple alternatively spliced transcript variants that encode different isoforms of this gene have been reported, but the full-length natures of only some have been determined.
Purification Method: | Affinity purification |
Gene ID: | 6103 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300,50% glycerol,pH7.3. |