The RPAP2 Polyclonal Antibody (CAB18500) is a valuable tool for researchers studying the RPAP2 protein, which is involved in RNA polymerase II assembly and transcription regulation. This antibody, produced in rabbits, has high specificity and sensitivity for detecting RPAP2 in human samples, making it ideal for use in Western blot applications. By targeting the RPAP2 protein, researchers can gain insights into its function and involvement in various cellular processes, including gene expression and RNA metabolism.RPAP2 is a key player in the assembly of the RNA polymerase II complex, which is essential for transcribing genes and regulating gene expression. Dysregulation of RPAP2 has been linked to abnormal transcription activity and altered gene expression patterns, highlighting its importance in cellular function and disease development.
Research on RPAP2 using this antibody can provide valuable information for understanding transcriptional control mechanisms and their implications in diseases such as cancer and developmental disorders.Overall, the RPAP2 Polyclonal Antibody (CAB18500) offers researchers a reliable tool for investigating the role of RPAP2 in various cellular processes and disease pathways, ultimately paving the way for potential therapeutic strategies targeting transcriptional dysregulation.
Antibody Name:
Anti-RPAP2 Antibody
Antibody SKU:
CAB18500
Antibody Size:
20uL, 50uL, 100uL
Application:
WB
Reactivity:
Rat
Host Species:
Rabbit
Immunogen:
Recombinant protein of human RPAP2.
Application:
WB
Recommended Dilution:
WB 1:500 - 1:2000
Reactivity:
Rat
Positive Samples:
Immunogen:
Recombinant protein of human RPAP2.
Purification Method:
Affinity purification
Storage Buffer:
Store at -20°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Isotype:
IgG
Sequence:
Email for sequence
Gene ID:
79871
Uniprot:
Q8IXW5
Cellular Location:
Calculated MW:
Observed MW:
Refer to figures
Synonyms:
C1orf82, Rtr1, RPAP2
Background:
UniProt Protein Function:
Protein phosphatase that displays CTD phosphatase activity and regulates transcription of snRNA genes. Recognizes and binds phosphorylated 'Ser-7' of the C-terminal heptapeptide repeat domain (CTD) of the largest RNA polymerase II subunit POLR2A, and mediates dephosphorylation of 'Ser-5' of the CTD, thereby promoting transcription of snRNA genes.
