The ROR2 Rabbit Monoclonal Antibody (CAB5120) is a valuable tool for researchers studying the ROR2 protein, a receptor tyrosine kinase involved in cell signaling and development. This antibody, generated in rabbits, exhibits high specificity and sensitivity when detecting ROR2 in human samples, making it ideal for use in Western blot applications.ROR2 plays a crucial role in various biological processes, including skeletal and cardiovascular development, making it a target of interest in developmental biology and regenerative medicine research. The ability of the ROR2 Rabbit Monoclonal Antibody to specifically bind to ROR2 enables researchers to study its expression and function in different cell types and experimental models, providing insights into its role in both normal and disease states.
Understanding the molecular mechanisms underlying ROR2 activity is essential for uncovering its potential therapeutic implications in conditions such as skeletal disorders, cancer, and cardiovascular diseases. The ROR2 Rabbit Monoclonal Antibody offers researchers a reliable tool for investigating the role of ROR2 in health and disease, opening new avenues for exploring targeted treatment strategies.
Product Name:
ROR2 Rabbit Monoclonal Antibody
SKU:
CAB5120
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Mouse
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 1-100 of human ROR2 (Q01974).
Cell membrane, Single-pass type I membrane protein.
Calculated MW:
105kDa
Observed MW:
105kDa
The protein encoded by this gene is a receptor protein tyrosine kinase and type I transmembrane protein that belongs to the ROR subfamily of cell surface receptors. The protein may be involved in the early formation of the chondrocytes and may be required for cartilage and growth plate development. Mutations in this gene can cause brachydactyly type B, a skeletal disorder characterized by hypoplasia/aplasia of distal phalanges and nails. In addition, mutations in this gene can cause the autosomal recessive form of Robinow syndrome, which is characterized by skeletal dysplasia with generalized limb bone shortening, segmental defects of the spine, brachydactyly, and a dysmorphic facial appearance.
Purification Method:
Affinity purification
Gene ID:
4920
Clone Number:
ARC1197
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3.
Western blot analysis of extracts of various cell lines, using ROR2 Rabbit mAb (CAB5120) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Enhanced Kit (AbGn00021).Exposure time: 90s.
