The ROR2 Polyclonal Antibody (CAB5620) is a valuable tool for researchers studying the ROR2 protein, a member of the receptor tyrosine kinase-like orphan receptor (ROR) family. This antibody, raised in rabbits, is highly specific to human samples and is validated for use in Western blot applications. By binding to the ROR2 protein, this antibody enables the detection and analysis of ROR2 in a variety of cell types.The ROR2 protein is known to play a crucial role in various biological processes, including skeletal development, cell migration, and tissue regeneration. Dysregulation of ROR2 has been linked to developmental disorders and certain types of cancer, making it a promising target for therapeutic interventions.
By studying the function and expression of ROR2 using this antibody, researchers can gain valuable insights into its role in health and disease.Overall, the ROR2 Polyclonal Antibody is a valuable tool for researchers interested in exploring the functions of the ROR2 protein in a wide range of biological contexts, including developmental biology, oncology, and regenerative medicine. Its high specificity and reliability make it an essential component of any research toolkit aimed at understanding the complex roles of ROR2 in cellular processes.
Product Name:
ROR2 Rabbit Polyclonal Antibody
SKU:
CAB5620
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 100-200 of human ROR2 (NP_004551.2).
Cell membrane, Single-pass type I membrane protein.
Calculated MW:
105kDa
Observed MW:
140kDa
The protein encoded by this gene is a receptor protein tyrosine kinase and type I transmembrane protein that belongs to the ROR subfamily of cell surface receptors. The protein may be involved in the early formation of the chondrocytes and may be required for cartilage and growth plate development. Mutations in this gene can cause brachydactyly type B, a skeletal disorder characterized by hypoplasia/aplasia of distal phalanges and nails. In addition, mutations in this gene can cause the autosomal recessive form of Robinow syndrome, which is characterized by skeletal dysplasia with generalized limb bone shortening, segmental defects of the spine, brachydactyly, and a dysmorphic facial appearance.
Purification Method:
Affinity purification
Gene ID:
4920
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of Mouse embryo, using ROR2 antibody (CAB5620) at 1:700 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 180s.
