The ROR2 Polyclonal Antibody (CAB17331) is a valuable tool for research related to the ROR2 protein, a receptor tyrosine kinase involved in various cellular processes, including development and tissue regeneration. This antibody, produced in rabbits, exhibits high specificity and sensitivity towards human samples, making it ideal for use in Western blotting and immunohistochemistry applications.ROR2 plays a crucial role in signaling pathways that regulate cell migration, proliferation, and differentiation, making it a key player in development and disease progression. Dysregulation of ROR2 has been implicated in a range of disorders, including skeletal abnormalities, cancer, and developmental defects.
Investigating the expression and function of ROR2 with this antibody can provide valuable insights into its role in these conditions.Researchers in the fields of developmental biology, cancer biology, and regenerative medicine will find the ROR2 Polyclonal Antibody (CAB17331) to be a valuable tool for their studies. Its ability to specifically detect ROR2 protein in various sample types makes it a reliable choice for investigating the mechanisms underlying ROR2-mediated cellular processes. Unlock the potential of your research with this high-quality antibody from Assay Genie.
Product Name:
ROR2 Rabbit Polyclonal Antibody
SKU:
CAB17331
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 300-400 of human ROR2 (NP_004551.2).
Cell membrane, Single-pass type I membrane protein.
Calculated MW:
105kDa
Observed MW:
145kDa
The protein encoded by this gene is a receptor protein tyrosine kinase and type I transmembrane protein that belongs to the ROR subfamily of cell surface receptors. The protein may be involved in the early formation of the chondrocytes and may be required for cartilage and growth plate development. Mutations in this gene can cause brachydactyly type B, a skeletal disorder characterized by hypoplasia/aplasia of distal phalanges and nails. In addition, mutations in this gene can cause the autosomal recessive form of Robinow syndrome, which is characterized by skeletal dysplasia with generalized limb bone shortening, segmental defects of the spine, brachydactyly, and a dysmorphic facial appearance.
Purification Method:
Affinity purification
Gene ID:
4920
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of lysates from rat small intestine, using ROR2 Rabbit pAb (CAB17331) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 30s.
