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ROR2 Rabbit Polyclonal Antibody (CAB17331)

SKU:
CAB17331
Product Type:
Antibody
Reactivity:
Rat
Host Species:
Rabbit
Isotype:
IgG
Antibody Type:
Polyclonal Antibody
Research Area:
Metabolism
€139 - €419
Frequently bought together:

Description

system_update_altDatasheetsystem_update_altMSDS
Product Name:ROR2 Rabbit Polyclonal Antibody
SKU:CAB17331
Size:20uL, 100uL
Isotype:IgG
Host Species:Rabbit
Reactivity:Rat
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 300-400 of human ROR2 (NP_004551.2).
Sequence:CMRI GIPA ERLG RYHQ CYNG SGMD YRGT ASTT KSGH QCQP WALQ HPHS HHLS STDF PELG GGHA YCRN PGGQ MEGP WCFT QNKN VRME LCDV PSCS PRDS S
Tested Applications:WB ELISA
Recommended Dilution:WB,1:500 - 1:2000
Synonyms:BDB; BDB1; NTRKR2; ROR2
Positive Sample:Rat small intestine
Conjugate:Unconjugated
Cellular Localization:Cell membrane, Single-pass type I membrane protein.
Calculated MW:105kDa
Observed MW:145kDa

The protein encoded by this gene is a receptor protein tyrosine kinase and type I transmembrane protein that belongs to the ROR subfamily of cell surface receptors. The protein may be involved in the early formation of the chondrocytes and may be required for cartilage and growth plate development. Mutations in this gene can cause brachydactyly type B, a skeletal disorder characterized by hypoplasia/aplasia of distal phalanges and nails. In addition, mutations in this gene can cause the autosomal recessive form of Robinow syndrome, which is characterized by skeletal dysplasia with generalized limb bone shortening, segmental defects of the spine, brachydactyly, and a dysmorphic facial appearance.

Purification Method:Affinity purification
Gene ID:4920
Storage Buffer:Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Product ImageWestern blot analysis of lysates from rat small intestine, using ROR2 Rabbit pAb (CAB17331) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 30s.

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