The ROR1 Polyclonal Antibody (CAB3315) from AssayGenie is a valuable tool for researchers studying the receptor tyrosine kinase-like orphan receptor 1 (ROR1) protein. This antibody, generated in rabbits, is highly specific and reactive with human samples, making it ideal for use in Western blot applications.ROR1 is a cell surface protein that is implicated in various cellular processes, including cell proliferation, survival, and migration. It plays a role in cancer development and has been identified as a potential therapeutic target in certain types of cancer.By targeting the ROR1 protein, researchers can investigate its role in cancer progression and potentially develop targeted therapies for ROR1-expressing cancers.
This antibody enables the detection and analysis of ROR1 in different cell types, providing valuable insights into its function and potential as a therapeutic target.With its high specificity and reactivity, the ROR1 Polyclonal Antibody (CAB3315) is a valuable tool for scientists working in the fields of oncology, cancer biology, and cell signaling. Its versatility in applications makes it a valuable addition to any research laboratory looking to study ROR1 and its role in cancer development.
Product Name:
ROR1 Rabbit Polyclonal Antibody
SKU:
CAB3315
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 24-403 of human ROR1 (NP_005003.2).
This gene encodes a receptor tyrosine kinase-like orphan receptor that modulates neurite growth in the central nervous system. The encoded protein is a glycosylated type I membrane protein that belongs to the ROR subfamily of cell surface receptors. It is a pseudokinase that lacks catalytic activity and may interact with the non-canonical Wnt signalling pathway. This gene is highly expressed during early embryonic development but expressed at very low levels in adult tissues. Increased expression of this gene is associated with B-cell chronic lymphocytic leukaemia. Alternative splicing results in multiple transcript variants encoding different isoforms.
Purification Method:
Affinity purification
Gene ID:
4919
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of lysates from Rat uterus, using ROR1 Rabbit pAb (CAB3315) at 1:800 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 90s.
