ROR1 Rabbit Polyclonal Antibody (CAB3315)
- SKU:
- CAB3315
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Research Area:
- Metabolism
Frequently bought together:
Description
Product Name: | ROR1 Rabbit Polyclonal Antibody |
SKU: | CAB3315 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Rat |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 24-403 of human ROR1 (NP_005003.2). |
Sequence: | ARGA AAQE TELS VSAE LVPT SSWN ISSE LNKD SYLT LDEP MNNI TTSL GQTA ELHC KVSG NPPP TIRW FKND APVV QEPR RLSF RSTI YGSR LRIR NLDT TDTG YFQC VATN GKEV VSST GVLF VKFG PPPT ASPG YSDE YEED GFCQ PYRG IACA RFIG NRTV YMES LHMQ GEIE NQIT AAFT MIGT SSHL SDKC SQFA IPSL CHYA FPYC DETS SVPK PRDL CRDE CEIL ENVL CQTE YIFA RSNP MILM RLKL PNCE DLPQ PESP EAAN CIRI GIPM ADPI NKNH KCYN STGV DYRG TVSV TKSG RQCQ PWNS QYPH THTF TALR FPEL NGGH SYCR NPGN QKEA PWCF TLDE NFKS DLCD IPAC DSKD SKEK NKME |
Tested Applications: | WB ELISA |
Recommended Dilution: | WB,1:500 - 1:1000 |
Synonyms: | NTRKR1; dJ537F10.1; ROR1 |
Positive Sample: | Rat uterus |
Conjugate: | Unconjugated |
Cellular Localization: | Membrane, Single-pass type I membrane protein. |
Calculated MW: | 104kDa |
Observed MW: | 135kDa |
This gene encodes a receptor tyrosine kinase-like orphan receptor that modulates neurite growth in the central nervous system. The encoded protein is a glycosylated type I membrane protein that belongs to the ROR subfamily of cell surface receptors. It is a pseudokinase that lacks catalytic activity and may interact with the non-canonical Wnt signalling pathway. This gene is highly expressed during early embryonic development but expressed at very low levels in adult tissues. Increased expression of this gene is associated with B-cell chronic lymphocytic leukaemia. Alternative splicing results in multiple transcript variants encoding different isoforms.
Purification Method: | Affinity purification |
Gene ID: | 4919 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3. |