The ROPN1L Polyclonal Antibody (PAC011888) is a valuable tool for researchers studying ROPN1L, a member of the ropporin family involved in sperm function. This antibody, generated in rabbits, is highly specific for human samples and is validated for use in Western blot applications. By binding to the ROPN1L protein, this antibody allows for the detection and analysis of ROPN1L in various cell types, making it an excellent choice for studies in reproductive biology and fertility research.
ROPN1L plays a crucial role in sperm development and function, making it a key target for investigations into male infertility and reproductive health. By understanding the functions and mechanisms of ROPN1L, researchers can gain insights into fertility issues and potentially develop new strategies for treating infertility. This antibody is a valuable tool for unraveling the mysteries of sperm biology and reproductive physiology.
ROPN1L: a member of the ropporin family. The encoded protein is a sperm protein. It interacts with A-kinase anchoring protein, AKAP3, through the amphipathic helix region of AKAP3. Type II regulatory subunit of cAMP-dependent protein kinase (PKARII) also binds to this helix domain of AKAP3, which allows PKARII to be targeted to specific subcellular compartments. It is suggested that sperm contains several proteins that bind to AKAPs in a manner similar to PKARII, and this encoded protein may be one of them. Alternatively spliced transcript variants encoding the same protein have been found for this gene.[provided by RefSeq, Jan 2011]Protein type: Protein kinase, regulatory subunitChromosomal Location of Human Ortholog: 5p15.2Cellular Component: cytoplasmMolecular Function: protein binding
UniProt Protein Details:
NCBI Summary:
This gene encodes a member of the ropporin family. The encoded protein is present in sperm and interacts with A-kinase anchoring protein, AKAP3, through the amphipathic helix region of AKAP3. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Oct 2014]
