ROMO1 Antibody (PACO29580)
- SKU:
- PACO29580
- Product Type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- ELISA
- IF
- Antibody Type:
- Polyclonal Antibody
- Conjugation:
- Unconjugated
Description
ROMO1 Antibody (PACO29580)
The ROMO1 Polyclonal Antibody (PAC029580) is a valuable tool for researchers studying ROMO1, a protein involved in regulating oxidative stress and cell death. This antibody, produced in rabbits, is highly specific to ROMO1 in human samples and is suitable for Western blot applications. By binding to ROMO1, researchers can accurately detect and analyze this protein in various cell types, making it an ideal choice for investigations in the fields of aging, cancer, and neurodegenerative diseases.ROMO1, also known as reactive oxygen species modulator 1, is a key player in controlling cellular redox balance and mitochondria function.
Dysregulation of ROMO1 has been linked to various diseases associated with oxidative stress, making it a promising target for therapeutic interventions. Understanding the role of ROMO1 in disease pathogenesis is crucial for developing effective treatments that target oxidative stress and mitochondrial dysfunction.Overall, the ROMO1 Polyclonal Antibody (PAC029580) offers researchers a reliable tool for studying the function of ROMO1 in different biological contexts, paving the way for new insights into disease mechanisms and potential treatment strategies.
| Antibody Name: | ROMO1 Antibody (PACO29580) |
| Antibody SKU: | PACO29580 |
| Size: | 50ug |
| Host Species: | Rabbit |
| Tested Applications: | ELISA, IF |
| Recommended Dilutions: | ELISA:1:2000-1:10000, IF:1:50-1:200 |
| Species Reactivity: | Human |
| Immunogen: | Recombinant Human Reactive oxygen species modulator 1 protein (45-79AA) |
| Form: | Liquid |
| Storage Buffer: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 |
| Purification Method: | >95%, Protein G purified |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Conjugate: | Non-conjugated |
 | Immunofluorescent analysis of MCF-7 cells using PACO29580 at dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L). |
| Background: | Induces production of reactive oxygen species (ROS) which are necessary for cell proliferation. May play a role in inducing oxidative DNA damage and replicative senescence. May play a role in the coordination of mitochondrial morphology and cell proliferation. |
| Synonyms: | Reactive oxygen species modulator 1 (ROS modulator 1) (Epididymis tissue protein Li 175) (Glyrichin) (Mitochondrial targeting GxxxG motif protein) (MTGM) (Protein MGR2 homolog), ROMO1, C20orf52 |
| UniProt Protein Function: | ROMO1: Induces production of reactive oxygen species (ROS) which are necessary for cell proliferation. May play a role in inducing oxidative DNA damage and replicative senescence. May play a role in the coordination of mitochondrial morphology and cell proliferation. Belongs to the MGR2 family. 2 isoforms of the human protein are produced by alternative splicing. |
| UniProt Protein Details: | Protein type:Cell cycle regulation; Membrane protein, integral; Mitochondrial Chromosomal Location of Human Ortholog: 20q11.22 Cellular Component: mitochondrion; mitochondrial inner membrane; integral to membrane Biological Process: positive regulation of cell proliferation; defense response to bacterium; replicative cell aging |
| UniProt Code: | P60602 |
| NCBI GenInfo Identifier: | 18152785 |
| NCBI Gene ID: | |
| NCBI Accession: | |
| Molecular Weight: | |
| NCBI Full Name: | reactive oxygen species modulator 1 |
| UniProt Protein Name: | Reactive oxygen species modulator 1 |
| UniProt Synonym Protein Names: | Epididymis tissue protein Li 175; Glyrichin; Mitochondrial targeting GxxxG motif protein; MTGM; Protein MGR2 homolog |
| Protein Family: | Transcriptional regulatory protein |
| UniProt Gene Name: | ROMO1Â Â |
| UniProt Entry Name: | ROMO1_HUMAN |
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