The ROCK2 Rabbit Monoclonal Antibody (CAB2395) is a highly specific tool for researchers studying the ROCK2 protein, an important regulator of cellular processes such as cell migration, apoptosis, and cytoskeletal dynamics. This antibody, produced in rabbits, exhibits strong reactivity with human samples and has been validated for use in Western blotting and immunofluorescence applications.ROCK2, a member of the Rho-associated coiled-coil containing protein kinase family, plays a key role in the regulation of actin cytoskeleton organization and cell motility. Dysregulation of ROCK2 signaling has been implicated in various diseases, including cancer and cardiovascular disorders.
By targeting the ROCK2 protein, researchers can gain insights into the molecular mechanisms underlying these pathologies and potentially identify new therapeutic targets.With its high specificity and sensitivity, the ROCK2 Rabbit Monoclonal Antibody (CAB2395) is an essential tool for investigations into the functions of ROCK2 in normal physiology and disease states. Its ability to detect ROCK2 protein expression in different cell types makes it an invaluable resource for studies in cell biology, cancer research, and drug development. Gain a deeper understanding of ROCK2 biology with this reliable and versatile antibody.
Product Name:
ROCK2 Rabbit Monoclonal Antibody
SKU:
CAB2395
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 1289-1388 of human ROCK2 (O75116).
The protein encoded by this gene is a serine/threonine kinase that regulates cytokinesis, smooth muscle contraction, the formation of actin stress fibers and focal adhesions, and the activation of the c-fos serum response element. This protein, which is an isozyme of ROCK1 is a target for the small GTPase Rho.
Purification Method:
Affinity purification
Gene ID:
9475
Clone Number:
ARC0744
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3.
Western blot analysis of various lysates using ROCK2 Rabbit mAb (CAB2395) at 1：1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 90s.
