The ROCK2 Polyclonal Antibody is a valuable tool for researchers studying the ROCK2 protein, a key regulator of cell migration and invasion. This antibody, generated in rabbits, is highly specific for the ROCK2 protein in human samples and has been validated for use in Western blotting applications. By detecting and analyzing the expression of ROCK2 in various cell types, this antibody is essential for investigations in the fields of cell biology, cancer research, and drug development.ROCK2, a member of the Rho-associated coiled-coil kinase family, plays a crucial role in controlling actin cytoskeleton dynamics and cell contractility.
Dysregulation of ROCK2 has been implicated in various diseases, including cancer, cardiovascular disorders, and neurological conditions. Understanding the function of ROCK2 is essential for developing targeted therapies to modulate cell migration and invasion in these disease contexts.By using the ROCK2 Polyclonal Antibody, researchers can gain valuable insights into the role of ROCK2 in cellular processes and disease pathogenesis. This antibody provides reliable detection and analysis of ROCK2 expression, making it a valuable tool for advancing research in cell biology and drug discovery.
Product Name:
ROCK2 Polyclonal Antibody
SKU:
CAB21715
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1109-1388 of human ROCK2 (NP_004841.2).
The protein encoded by this gene is a serine/threonine kinase that regulates cytokinesis, smooth muscle contraction, the formation of actin stress fibers and focal adhesions, and the activation of the c-fos serum response element. This protein, which is an isozyme of ROCK1 is a target for the small GTPase Rho.
Purification Method:
Affinity purification
Gene ID:
9475
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of lysates from Human lung using ROCK2 Rabbit pAb(CAB21715) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25 μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Enhanced Kit (AbGn00021).Exposure time: 90s.
