The ROCK2 Polyclonal Antibody (CAB5698) is a valuable tool for researchers studying the ROCK2 protein, a key regulator of cell migration, proliferation, and cytoskeletal dynamics. This antibody, produced in rabbits, shows high reactivity with human samples and has been validated for use in Western blot applications. By binding specifically to the ROCK2 protein, this antibody enables accurate detection and analysis in a variety of cell types, making it ideal for investigations in cell biology, cancer research, and drug development.ROCK2, a member of the Rho-associated coiled-coil containing protein kinase family, plays a crucial role in various cellular processes including cell adhesion, motility, and cell division.
Its dysregulation has been implicated in numerous diseases such as cancer, cardiovascular disorders, and neurological conditions. By understanding the function and signaling pathways of ROCK2, researchers can uncover new therapeutic targets and develop innovative treatments for these diseases.Overall, the ROCK2 Polyclonal Antibody (CAB5698) is a valuable resource for researchers aiming to elucidate the role of ROCK2 in physiological and pathological conditions, ultimately leading to the development of novel therapeutic strategies.
Product Name:
ROCK2 Rabbit Polyclonal Antibody
SKU:
CAB5698
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1109-1388 of human ROCK2 (NP_004841.2).
The protein encoded by this gene is a serine/threonine kinase that regulates cytokinesis, smooth muscle contraction, the formation of actin stress fibers and focal adhesions, and the activation of the c-fos serum response element. This protein, which is an isozyme of ROCK1 is a target for the small GTPase Rho.
Purification Method:
Affinity purification
Gene ID:
9475
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300,50% glycerol,pH7.3.
Western blot analysis of various lysates using ROCK2 Rabbit pAb (CAB5698) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 180s.
