The ROBO4 Polyclonal Antibody (CAB9876) is a valuable tool for researchers studying ROBO4, a vascular cell adhesion molecule implicated in angiogenesis and vascular development. This antibody, produced in rabbits, demonstrates high reactivity with human samples and is validated for use in various research applications, including Western blotting. By binding to the ROBO4 protein, this antibody enables precise detection and analysis in different cell types, making it an ideal choice for investigations in vascular biology and cardiovascular disease research.ROBO4, also known as Roundabout homolog 4, plays a crucial role in regulating blood vessel formation and stability, making it a promising target for studying angiogenesis and vascular abnormalities.
Understanding the functions and mechanisms of ROBO4 can provide insights into diseases such as cancer, cardiovascular disorders, and vascular malformations, paving the way for the development of targeted therapeutics and treatment strategies. Researchers focused on vascular biology and related fields will find the ROBO4 Polyclonal Antibody to be a valuable asset in their studies.
Product Name:
ROBO4 Rabbit Polyclonal Antibody
SKU:
CAB9876
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 848-1007 of human ROBO4 (NP_061928.4).
Predicted to enable cell-cell adhesion mediator activity. Involved in angiogenesis and establishment of endothelial barrier. Located in extracellular exosome. Implicated in aortic valve disease 3.
Purification Method:
Affinity purification
Gene ID:
54538
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of extracts of various cell lines, using ROBO4 antibody (CAB9876) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 30s.
