ROBO1 Rabbit Polyclonal Antibody (CAB15313)
- SKU:
- CAB15313
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Biology
Frequently bought together:
Description
Product Name: | ROBO1 Rabbit Polyclonal Antibody |
SKU: | CAB15313 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse,Rat |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1452-1651 of human ROBO1 (NP_002932.1). |
Sequence: | AAVM QKTR PAKK LKHQ PGHL RRET YTDD LPPP PVPP PAIK SPTA QSKT QLEV RPVV VPKL PSMD ARTD RSSD RKGS SYKG REVL DGRQ VVDM RTNP GDPR EAQE QQND GKGR GNKA AKRD LPPA KTHL IQED ILPY CRPT FPTS NNPR DPSS SSSM SSRG SGSR QREQ ANVG RRNI AEMQ VLGG YERG EDNN EELE ETES |
Tested Applications: | WB IF/ICC ELISA |
Recommended Dilution: | WB,1:200 - 1:2000 IF/ICC,1:50 - 1:200 |
Synonyms: | NORS; NYS8; SAX3; CPHD8; DUTT1; ROBO1 |
Positive Sample: | 293T,U-251MG,HeLa,293T,U-251MG,HeLa,Mouse brain,Rat brain |
Conjugate: | Unconjugated |
Cellular Localization: | Cell membrane, Cell projection, Single-pass type I membrane protein, axon. |
Calculated MW: | 181kDa |
Observed MW: | 270kDa |
Bilateral symmetric nervous systems have special midline structures that establish a partition between the two mirror image halves. Some axons project toward and across the midline in response to long-range chemoattractants emanating from the midline. The product of this gene is a member of the immunoglobulin gene superfamily and encodes an integral membrane protein that functions in axon guidance and neuronal precursor cell migration. This receptor is activated by SLIT-family proteins, resulting in a repulsive effect on glioma cell guidance in the developing brain. A related gene is located at an adjacent region on chromosome 3. Multiple transcript variants encoding different isoforms have been found for this gene.
Purification Method: | Affinity purification |
Gene ID: | 6091 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3. |