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MRM3 Rabbit Polyclonal Antibody (CAB4816)

SKU:
CAB4816
Product Type:
Antibody
Antibody Type:
Polyclonal Antibody
Reactivity:
Human
Host Species:
Rabbit
Isotype:
IgG
Synonyms:
MRM3
RMTL1
RNMTL1
Research Area:
Epigenetics and Nuclear Signaling
  • Epigenetics and Nuclear Signaling Antibodies 3 Anti-MRM3 Antibody CAB4816
  • Epigenetics and Nuclear Signaling Antibodies 3 Anti-MRM3 Antibody CAB4816
€139 - €419
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Description

system_update_altDatasheetsystem_update_altMSDS
Product Name:MRM3 Rabbit Polyclonal Antibody
SKU:CAB4816
Size:20uL, 100uL
Isotype:IgG
Host Species:Rabbit
Reactivity:Human
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 1-420 of human MRM3 (NP_060616.1).
Sequence:MAAL VRPA RFVV RPLL QVVQ AWDL DARR WVRA LRRS PVKV VFPS GEVV EQKR APGK QPRK APSE ASAQ EQRE KQPL EESA SRAP STWE ESGL RYDK AYPG DRRL SSVM TIVK SRPF REKQ GKIL LEGR RLIS DALK AGAV PKMF FFSR LEYL KELP VDKL KGVS LIKV KFED IKDW SDLV TPQG IMGI FAKP DHVK MTYP KTQL QHSL PLLL ICDN LRDP GNLG TILR SAAG AGCS KVLL TKGC VDAW EPKV LRAG MGAH FRMP IINN LEWE TVPN YLPP DTRV YVAD NCGL YAQA EMSN KASD HGWV CDQR VMKF HKYE EEED VETG ASQD WLPH VEVQ SYDS DWTE APAA VVIG GETY GVSL ESLQ LAES TGGK RLLI PVVP GVDS LNSA MAAS ILLF EGKR QLRG RAED LSRD RSYH
Tested Applications:WB ELISA
Recommended Dilution:WB,1:500 - 1:2000
Synonyms:RMTL1; RNMTL1; MRM3
Positive Sample:U-87MG,HepG2,293T
Conjugate:Unconjugated
Cellular Localization:Mitochondrion.
Calculated MW:47kDa
Observed MW:47kDa

Efficient translation of mitochondrial-derived transcripts requires proper assembly of the large subunit of the mitochondrial ribosome. Central to the biogenesis of this large subunit is the A-loop of mitochondrial 16S rRNA, which is modified by three rRNA methyltransferases located near mtDNA nucleoids. The protein encoded by this gene methylates G(1370) of 16S rRNA, and this modification is necessary for proper ribosomal large subnit assembly. Two transcript variants encoding different isoforms have been found for this gene.

Purification Method:Affinity purification
Gene ID:55178
Storage Buffer:Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Product ImageWestern blot analysis of various lysates using MRM3 Rabbit pAb (CAB4816) at 1:3000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 30s.

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